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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LASS3
All Species:
4.55
Human Site:
T357
Identified Species:
10
UniProt:
Q8IU89
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU89
NP_849164.2
383
46217
T357
E
E
E
E
E
E
A
T
K
G
K
E
M
D
C
Chimpanzee
Pan troglodytes
XP_001141298
383
46214
T357
E
E
E
E
E
E
A
T
K
G
K
D
M
D
C
Rhesus Macaque
Macaca mulatta
XP_001082667
385
46517
D357
E
E
E
E
E
E
E
D
G
T
K
G
K
E
M
Dog
Lupus familis
XP_849881
457
54949
E423
E
E
E
E
E
E
E
E
E
E
E
E
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q924Z4
380
45006
A358
G
E
E
T
A
A
G
A
G
A
K
S
R
L
L
Rat
Rattus norvegicus
NP_001121033
391
47216
E357
E
E
E
E
E
E
E
E
E
E
E
E
E
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519596
334
40121
I327
G
Y
Y
I
L
K
I
I
K
K
F
L
F
V
K
Chicken
Gallus gallus
XP_424275
286
34432
R279
S
V
A
F
F
I
T
R
I
I
L
F
P
F
W
Frog
Xenopus laevis
NP_001085735
372
43975
N358
N
E
D
H
S
L
T
N
G
D
G
K
R
S
I
Zebra Danio
Brachydanio rerio
XP_694530
380
45048
D360
G
E
T
S
M
T
E
D
N
D
E
H
V
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6NQI8
308
36530
E301
E
D
V
R
S
D
S
E
G
E
D
E
H
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.5
74.8
N.A.
51.4
76.4
N.A.
71.2
46.7
50.6
52.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.1
79.4
N.A.
67.6
86.6
N.A.
78
55
69.4
70.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
46.6
46.6
N.A.
20
46.6
N.A.
6.6
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
66.6
N.A.
20
66.6
N.A.
13.3
0
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
19
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
10
10
0
0
10
0
19
0
19
10
10
0
19
10
% D
% Glu:
55
73
55
46
46
46
37
28
19
28
28
37
19
37
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
0
10
10
10
10
0
% F
% Gly:
28
0
0
0
0
0
10
0
37
19
10
10
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
10
0
10
10
10
10
10
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
10
0
0
28
10
37
10
10
10
10
% K
% Leu:
0
0
0
0
10
10
0
0
0
0
10
10
0
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
19
0
10
% M
% Asn:
10
0
0
0
0
0
0
10
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
0
0
19
0
0
% R
% Ser:
10
0
0
10
19
0
10
0
0
0
0
10
0
10
0
% S
% Thr:
0
0
10
10
0
10
19
19
0
10
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
10
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _