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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALHM1
All Species:
22.65
Human Site:
Y342
Identified Species:
55.37
UniProt:
Q8IU99
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IU99
NP_001001412.3
346
38264
Y342
P
R
K
E
V
A
T
Y
F
S
K
V
_
_
_
Chimpanzee
Pan troglodytes
XP_521596
346
38229
Y342
P
R
K
E
V
A
T
Y
F
S
K
V
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001113863
345
38166
Y341
P
R
K
E
V
A
T
Y
F
S
K
V
_
_
_
Dog
Lupus familis
XP_544001
344
37845
Y340
P
R
K
E
V
A
T
Y
F
S
G
V
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEC4
323
35805
Rat
Rattus norvegicus
Q5RJQ8
323
35913
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512111
444
48765
Y337
P
R
K
E
V
A
V
Y
Y
S
K
T
A
G
N
Chicken
Gallus gallus
XP_426534
342
38539
Y338
P
R
R
E
A
V
A
Y
Y
S
G
V
_
_
_
Frog
Xenopus laevis
NP_001086556
319
35970
Zebra Danio
Brachydanio rerio
XP_001344294
346
39731
Y342
T
K
K
K
A
V
V
Y
Y
S
K
V
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.6
94.2
N.A.
26.8
27.4
N.A.
59.4
70.5
27.4
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.5
96.5
N.A.
45
45.3
N.A.
65.3
78
47.1
72.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
91.6
N.A.
0
0
N.A.
60
50
0
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
91.6
N.A.
0
0
N.A.
73.3
66.6
0
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
50
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
20
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
60
10
0
0
0
0
0
0
50
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
60
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
70
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
40
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
50
20
20
0
0
0
0
60
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
30
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
60
60
60
% _