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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA9 All Species: 42.12
Human Site: S1448 Identified Species: 92.67
UniProt: Q8IUA7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUA7 NP_525022.2 1624 184362 S1448 V V L L D E P S T G M D P E G
Chimpanzee Pan troglodytes XP_001146190 1594 180484 S1418 V V L L D E P S T G M D P E G
Rhesus Macaque Macaca mulatta XP_001082756 1615 183008 S1439 V V L L D E P S T G M D P E G
Dog Lupus familis XP_853718 1625 184408 S1449 V V L L D E P S T G M D P E G
Cat Felis silvestris
Mouse Mus musculus Q8K449 1623 183126 S1447 V V L L D E P S T G M D P E G
Rat Rattus norvegicus Q8CF82 1642 185792 S1460 V T L L D E P S T G M D P R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509469 1722 195635 S1540 I T L L D E P S T G M D P K A
Chicken Gallus gallus XP_415691 1546 175373 S1370 V L L L D E P S T G M D P N G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001918691 1654 185749 S1460 I V L L D E P S T G M D P K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 T1530 M I I L D E P T A G I D P K A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 S1617 I V I L D E P S T G M D P V A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 94.5 85.5 N.A. 78.6 41.5 N.A. 39.9 45.5 N.A. 41.8 N.A. N.A. N.A. 22 N.A.
Protein Similarity: 100 97.5 96.7 92 N.A. 88.2 61.9 N.A. 60.1 63.2 N.A. 61.1 N.A. N.A. N.A. 43 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 80 N.A. 73.3 86.6 N.A. 80 N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 80 N.A. 86.6 93.3 N.A. 93.3 N.A. N.A. N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 73.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 86.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 37 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 100 0 0 0 0 0 0 100 0 0 0 % D
% Glu: 0 0 0 0 0 100 0 0 0 0 0 0 0 46 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 55 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 28 10 19 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % K
% Leu: 0 10 82 100 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 91 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 100 0 0 0 0 0 100 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 91 0 0 0 0 0 0 10 % S
% Thr: 0 19 0 0 0 0 0 10 91 0 0 0 0 0 0 % T
% Val: 64 64 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _