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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA9 All Species: 20
Human Site: T832 Identified Species: 44
UniProt: Q8IUA7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUA7 NP_525022.2 1624 184362 T832 V L S S F H E T R K T I S G V
Chimpanzee Pan troglodytes XP_001146190 1594 180484 T832 V L S S F H E T R K T I S G V
Rhesus Macaque Macaca mulatta XP_001082756 1615 183008 T823 V F S S F H E T R K T I S G M
Dog Lupus familis XP_853718 1625 184408 T833 V L S S F K E T K K S I S G M
Cat Felis silvestris
Mouse Mus musculus Q8K449 1623 183126 G832 V L S L D S S G S S V S G M A
Rat Rattus norvegicus Q8CF82 1642 185792 T829 S L L I L S E T K A S L V S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509469 1722 195635 T909 S L L I L S E T K S S A V S T
Chicken Gallus gallus XP_415691 1546 175373 T773 L S D T G R M T L S S W A L W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001918691 1654 185749 S832 R L L T F S D S R Q D T V T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 I893 A S R Q N S R I S H N S R N A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 C898 D T K S S L V C I G S N Q K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 94.5 85.5 N.A. 78.6 41.5 N.A. 39.9 45.5 N.A. 41.8 N.A. N.A. N.A. 22 N.A.
Protein Similarity: 100 97.5 96.7 92 N.A. 88.2 61.9 N.A. 60.1 63.2 N.A. 61.1 N.A. N.A. N.A. 43 N.A.
P-Site Identity: 100 100 86.6 73.3 N.A. 20 20 N.A. 20 6.6 N.A. 20 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 20 40 N.A. 33.3 33.3 N.A. 46.6 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 10 0 10 10 0 19 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 10 0 10 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 55 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 46 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 10 0 10 0 0 10 37 10 % G
% His: 0 0 0 0 0 28 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 10 10 0 0 37 0 0 0 % I
% Lys: 0 0 10 0 0 10 0 0 28 37 0 0 0 10 0 % K
% Leu: 10 64 28 10 19 10 0 0 10 0 0 10 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 19 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 10 10 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 10 0 0 10 0 0 % Q
% Arg: 10 0 10 0 0 10 10 0 37 0 0 0 10 0 0 % R
% Ser: 19 19 46 46 10 46 10 10 19 28 46 19 37 19 10 % S
% Thr: 0 10 0 19 0 0 0 64 0 0 28 10 0 10 19 % T
% Val: 46 0 0 0 0 0 10 0 0 0 10 0 28 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _