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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF135
All Species:
12.42
Human Site:
S214
Identified Species:
34.17
UniProt:
Q8IUD6
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUD6
NP_115698.3
432
47888
S214
I
Q
E
K
L
Q
E
S
V
T
W
K
E
A
P
Chimpanzee
Pan troglodytes
Q5D7J1
493
56253
T225
E
T
E
M
V
Q
Q
T
Q
S
V
R
E
L
I
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
S215
E
E
E
D
I
L
K
S
L
T
K
S
E
T
E
Dog
Lupus familis
XP_537734
397
44059
W187
K
L
Q
E
N
F
T
W
K
G
A
L
E
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWS1
417
46443
K199
N
L
E
E
I
Q
E
K
L
Q
G
S
V
P
G
Rat
Rattus norvegicus
Q5M929
415
45993
T202
D
L
E
K
I
Q
E
T
L
Q
G
S
V
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511163
412
45810
T198
L
K
K
K
L
Q
E
T
L
I
W
A
E
A
P
Chicken
Gallus gallus
XP_415653
633
71406
N356
D
V
V
K
L
A
V
N
V
S
V
D
K
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092898
445
50189
T219
R
S
S
A
A
R
K
T
F
S
K
R
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.5
21.3
65
N.A.
59
61.5
N.A.
38.6
25.1
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
43
40.8
73.8
N.A.
70.3
73.1
N.A.
55
39.4
N.A.
42.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
26.6
6.6
N.A.
20
26.6
N.A.
53.3
20
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
53.3
20
N.A.
40
46.6
N.A.
86.6
40
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
12
0
0
0
0
12
12
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
23
12
56
23
0
0
45
0
0
0
0
0
56
12
12
% E
% Phe:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
23
0
0
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
12
0
0
0
34
0
0
0
0
12
0
0
0
0
12
% I
% Lys:
12
12
12
45
0
0
23
12
12
0
23
12
12
12
12
% K
% Leu:
12
34
0
0
34
12
0
0
45
0
0
12
12
12
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
23
% P
% Gln:
0
12
12
0
0
56
12
0
12
23
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
12
0
0
0
0
0
23
0
12
0
% R
% Ser:
0
12
12
0
0
0
0
23
0
34
0
34
0
0
0
% S
% Thr:
0
12
0
0
0
0
12
45
0
23
0
0
0
23
12
% T
% Val:
0
12
12
0
12
0
12
0
23
0
23
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
23
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _