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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST2H2AB
All Species:
44.85
Human Site:
S20
Identified Species:
82.22
UniProt:
Q8IUE6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUE6
NP_778235.1
130
13995
S20
A
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Chimpanzee
Pan troglodytes
XP_001137950
130
14103
S20
T
K
A
K
T
R
S
S
R
A
G
L
Q
F
P
Rhesus Macaque
Macaca mulatta
XP_001096671
130
14103
S20
A
K
A
K
T
R
S
S
R
A
G
L
Q
F
P
Dog
Lupus familis
XP_540293
193
20810
S83
A
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64522
130
13995
S20
A
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Rat
Rattus norvegicus
P02262
130
14059
S20
A
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513730
130
14089
S20
A
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Chicken
Gallus gallus
P02263
129
13922
S20
A
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Frog
Xenopus laevis
P06897
130
13948
S20
A
K
A
K
T
R
S
S
R
A
G
L
Q
F
P
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
S20
A
K
A
K
T
R
S
S
R
A
G
L
Q
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
L23
S
R
S
N
R
A
G
L
Q
F
P
V
G
R
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P09588
127
13386
S21
G
K
A
K
S
R
S
S
R
A
G
L
Q
F
P
Sea Urchin
Strong. purpuratus
P16886
126
13432
A20
A
K
A
K
S
R
S
A
R
A
G
L
Q
F
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
94.6
67.3
N.A.
99.2
95.3
N.A.
95.3
95.3
94.6
86.6
N.A.
86.9
N.A.
84.6
90
Protein Similarity:
100
95.3
96.9
67.3
N.A.
100
96.1
N.A.
96.9
96.9
96.9
89.4
N.A.
91.5
N.A.
87.6
92.3
P-Site Identity:
100
86.6
93.3
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
0
N.A.
93.3
93.3
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
33.3
N.A.
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
93
0
0
8
0
8
0
93
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
93
0
% F
% Gly:
8
0
0
0
0
0
8
0
0
0
93
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
93
0
93
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
93
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
93
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
93
0
0
% Q
% Arg:
0
8
0
0
8
93
0
0
93
0
0
0
0
8
0
% R
% Ser:
8
0
8
0
62
0
93
85
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _