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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MINA
All Species:
24.24
Human Site:
S422
Identified Species:
44.44
UniProt:
Q8IUF8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUF8
NP_001035998.1
465
52800
S422
H
G
L
R
F
P
L
S
H
L
D
A
L
K
Q
Chimpanzee
Pan troglodytes
XP_001139760
465
52766
S422
H
G
L
R
F
P
L
S
H
L
D
A
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001086033
465
52787
S422
H
G
L
R
F
P
L
S
H
L
D
A
L
K
Q
Dog
Lupus familis
XP_535711
463
51843
H421
G
L
R
F
P
L
S
H
M
D
A
L
K
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CD15
465
53499
S422
F
G
L
R
F
P
L
S
H
V
D
A
L
K
Q
Rat
Rattus norvegicus
Q8CFC1
465
53197
S422
Y
G
L
R
F
P
L
S
Y
V
D
A
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519133
464
53202
S421
H
G
L
R
F
P
L
S
H
M
D
A
L
K
Q
Chicken
Gallus gallus
Q5ZMM1
601
65667
E546
K
E
E
P
K
Y
L
E
I
D
P
E
Y
T
D
Frog
Xenopus laevis
NP_001086856
461
52506
A419
L
R
F
P
L
P
Y
A
N
A
L
K
R
I
W
Zebra Danio
Brachydanio rerio
A3KP59
544
61498
I495
F
E
M
K
T
E
H
I
D
A
M
E
F
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4H4
653
73079
Y597
D
Y
C
K
Y
E
P
Y
F
M
E
I
L
P
E
Honey Bee
Apis mellifera
XP_395039
495
58336
P446
E
V
S
E
E
F
I
P
A
I
R
K
M
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789366
511
58332
H445
L
H
N
S
H
L
E
H
M
M
C
S
E
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.6
78.7
N.A.
76.5
79.5
N.A.
77.6
28.1
53.9
28.6
N.A.
22.5
28.8
N.A.
38.1
Protein Similarity:
100
99.5
98.2
86.2
N.A.
86.4
88.1
N.A.
86.4
41.9
70.7
45.7
N.A.
35.9
46.6
N.A.
57.5
P-Site Identity:
100
100
100
0
N.A.
86.6
80
N.A.
93.3
6.6
6.6
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
100
N.A.
100
6.6
20
13.3
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
16
8
47
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
16
47
0
0
0
8
% D
% Glu:
8
16
8
8
8
16
8
8
0
0
8
16
8
0
8
% E
% Phe:
16
0
8
8
47
8
0
0
8
0
0
0
8
0
0
% F
% Gly:
8
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
31
8
0
0
8
0
8
16
39
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
8
8
0
8
0
16
16
% I
% Lys:
8
0
0
16
8
0
0
0
0
0
0
16
8
47
8
% K
% Leu:
16
8
47
0
8
16
54
0
0
24
8
8
54
8
8
% L
% Met:
0
0
8
0
0
0
0
0
16
24
8
0
8
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
16
8
54
8
8
0
0
8
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
47
% Q
% Arg:
0
8
8
47
0
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
0
8
8
0
0
8
47
0
0
0
8
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
8
0
0
0
0
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
8
8
0
0
8
8
8
8
8
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _