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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MINA All Species: 11.21
Human Site: S451 Identified Species: 20.56
UniProt: Q8IUF8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUF8 NP_001035998.1 465 52800 S451 T T D E E K E S L V L S L W T
Chimpanzee Pan troglodytes XP_001139760 465 52766 S451 T T D E E K E S L V L S L W T
Rhesus Macaque Macaca mulatta XP_001086033 465 52787 S451 T T D E E R E S L V L S L W T
Dog Lupus familis XP_535711 463 51843 L450 T D E E K E N L V L S L W T E
Cat Felis silvestris
Mouse Mus musculus Q8CD15 465 53499 N451 D T D E E K E N L A L S L W S
Rat Rattus norvegicus Q8CFC1 465 53197 N451 G T D E E K E N L A V S L W T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519133 464 53202 N450 N T D A E K E N L V V S L W T
Chicken Gallus gallus Q5ZMM1 601 65667 A575 V D T L P C D A L E D K I S L
Frog Xenopus laevis NP_001086856 461 52506 A448 D E D K E N L A L S L W T E G
Zebra Danio Brachydanio rerio A3KP59 544 61498 S524 E T A E A K M S L A E L L F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K4H4 653 73079 P626 Y L T I D Q L P L E S S A R K
Honey Bee Apis mellifera XP_395039 495 58336 I475 G E D N K I Q I V K D L W E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789366 511 58332 P474 L R A L Q E C P Q S W R N V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.6 78.7 N.A. 76.5 79.5 N.A. 77.6 28.1 53.9 28.6 N.A. 22.5 28.8 N.A. 38.1
Protein Similarity: 100 99.5 98.2 86.2 N.A. 86.4 88.1 N.A. 86.4 41.9 70.7 45.7 N.A. 35.9 46.6 N.A. 57.5
P-Site Identity: 100 100 93.3 13.3 N.A. 73.3 73.3 N.A. 73.3 6.6 26.6 40 N.A. 13.3 6.6 N.A. 0
P-Site Similarity: 100 100 100 46.6 N.A. 86.6 86.6 N.A. 86.6 26.6 40 46.6 N.A. 26.6 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 8 0 0 16 0 24 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % C
% Asp: 16 16 62 0 8 0 8 0 0 0 16 0 0 0 0 % D
% Glu: 8 16 8 54 54 16 47 0 0 16 8 0 0 16 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 8 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 8 16 47 0 0 0 8 0 8 0 0 16 % K
% Leu: 8 8 0 16 0 0 16 8 77 8 39 24 54 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 8 8 24 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 8 0 0 16 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 8 8 0 8 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 8 0 0 0 0 0 8 0 8 0 % R
% Ser: 0 0 0 0 0 0 0 31 0 16 16 54 0 8 16 % S
% Thr: 31 54 16 0 0 0 0 0 0 0 0 0 8 8 39 % T
% Val: 8 0 0 0 0 0 0 0 16 31 16 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 8 16 47 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _