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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREG2 All Species: 2.12
Human Site: T113 Identified Species: 5.19
UniProt: Q8IUH2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUH2 NP_722578.1 290 32109 T113 Y R R E G G Q T A S A P P G P
Chimpanzee Pan troglodytes XP_515663 290 32056 A113 Y R R E G G Q A A G A P P G P
Rhesus Macaque Macaca mulatta XP_001107073 290 31847 A113 Y R R E G G Q A A G A P P G P
Dog Lupus familis XP_854297 180 20555 G15 G G P R L R P G T A R F L A H
Cat Felis silvestris
Mouse Mus musculus Q8BGC9 288 31746 S111 S Y R R E S G S S E A S P G P
Rat Rattus norvegicus NP_001099436 220 24369 G55 P L P P R D D G P R V A R F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJ73 192 21088 A27 I P P P E E A A R M A R F V L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796937 218 23864 A53 F I D K A R R A R Y M V H K A
Poplar Tree Populus trichocarpa XP_002299070 191 21144 D26 L L L I N K P D P N D P A A S
Maize Zea mays NP_001148752 210 22772 R45 S E A T A T A R W L A A Q N T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 93.4 54.1 N.A. 84.1 30.6 N.A. N.A. 25.1 N.A. N.A. N.A. N.A. N.A. N.A. 31.7
Protein Similarity: 100 98.9 96.2 57.2 N.A. 90 48.6 N.A. N.A. 39.6 N.A. N.A. N.A. N.A. N.A. N.A. 46.9
P-Site Identity: 100 86.6 86.6 0 N.A. 33.3 0 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 86.6 86.6 6.6 N.A. 46.6 0 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 25.5 30.6 N.A. N.A. N.A. N.A.
Protein Similarity: 39.6 43.4 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 20 0 20 40 30 10 60 20 10 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 10 10 10 0 0 10 0 0 0 0 % D
% Glu: 0 10 0 30 20 10 0 0 0 10 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 10 10 10 0 % F
% Gly: 10 10 0 0 30 30 10 20 0 20 0 0 0 40 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 10 0 0 0 0 0 0 0 10 0 % K
% Leu: 10 20 10 0 10 0 0 0 0 10 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 10 0 0 0 10 0 % N
% Pro: 10 10 30 20 0 0 20 0 20 0 0 40 40 0 40 % P
% Gln: 0 0 0 0 0 0 30 0 0 0 0 0 10 0 0 % Q
% Arg: 0 30 40 20 10 20 10 10 20 10 10 10 10 0 0 % R
% Ser: 20 0 0 0 0 10 0 10 10 10 0 10 0 0 10 % S
% Thr: 0 0 0 10 0 10 0 10 10 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 30 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _