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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CREG2
All Species:
12.73
Human Site:
Y282
Identified Species:
31.11
UniProt:
Q8IUH2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUH2
NP_722578.1
290
32109
Y282
S
S
I
S
R
E
E
Y
F
K
A
V
P
R
K
Chimpanzee
Pan troglodytes
XP_515663
290
32056
Y282
S
N
I
S
R
E
E
Y
F
K
A
V
P
R
K
Rhesus Macaque
Macaca mulatta
XP_001107073
290
31847
Y282
S
N
I
S
K
E
E
Y
F
K
A
V
P
R
K
Dog
Lupus familis
XP_854297
180
20555
F173
D
I
S
R
D
E
Y
F
R
A
V
P
R
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGC9
288
31746
Y280
S
D
I
P
R
E
E
Y
F
K
A
A
P
R
K
Rat
Rattus norvegicus
NP_001099436
220
24369
E213
P
K
V
V
T
P
E
E
Y
F
N
V
T
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ73
192
21088
E185
G
L
K
I
V
T
P
E
E
Y
Y
N
V
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796937
218
23864
E211
G
G
S
S
L
S
V
E
D
Y
Y
K
A
T
P
Poplar Tree
Populus trichocarpa
XP_002299070
191
21144
V184
G
G
P
K
P
L
T
V
D
Q
Y
L
H
Y
K
Maize
Zea mays
NP_001148752
210
22772
N203
Q
Y
L
E
F
G
R
N
Q
G
S
L
M
Y
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
93.4
54.1
N.A.
84.1
30.6
N.A.
N.A.
25.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
100
98.9
96.2
57.2
N.A.
90
48.6
N.A.
N.A.
39.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.9
P-Site Identity:
100
93.3
86.6
6.6
N.A.
80
13.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
80
33.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
25.5
30.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.6
43.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
40
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
10
0
0
0
20
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
50
50
30
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
40
10
0
0
0
0
0
% F
% Gly:
30
20
0
0
0
10
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
40
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
10
10
0
0
0
0
40
0
10
0
20
50
% K
% Leu:
0
10
10
0
10
10
0
0
0
0
0
20
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
20
0
0
0
0
0
10
0
0
10
10
0
0
0
% N
% Pro:
10
0
10
10
10
10
10
0
0
0
0
10
40
0
20
% P
% Gln:
10
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% Q
% Arg:
0
0
0
10
30
0
10
0
10
0
0
0
10
40
0
% R
% Ser:
40
10
20
40
0
10
0
0
0
0
10
0
0
0
10
% S
% Thr:
0
0
0
0
10
10
10
0
0
0
0
0
10
10
0
% T
% Val:
0
0
10
10
10
0
10
10
0
0
10
40
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
40
10
20
30
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _