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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC13 All Species: 24.55
Human Site: S174 Identified Species: 41.54
UniProt: Q8IUH4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUH4 NP_001001483.1 622 70861 S174 Y L I S K G Q S V N M T D V N
Chimpanzee Pan troglodytes XP_508324 622 70862 S174 Y L I S K G Q S V N M T D V N
Rhesus Macaque Macaca mulatta XP_001096184 618 70464 S174 Y L I S K R Q S V N M T D V N
Dog Lupus familis XP_854853 673 77171 S225 Y L I S K G Q S V N M T D L N
Cat Felis silvestris
Mouse Mus musculus Q9CWU2 622 70871 S174 Y L I S K G Q S V N M T D V N
Rat Rattus norvegicus NP_001034126 622 70868 S174 Y L I P K G Q S V N M T D V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506180 611 68870 V169 F Y I S K G A V V D Q L G G D
Chicken Gallus gallus NP_001025916 622 71511 D172 Y L I A K G Q D V D M M D Q N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001918491 645 71421 E197 Y L M A K G Q E V D L P D L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648824 637 71280 D170 Y F I A K G V D P D L Q D R G
Honey Bee Apis mellifera XP_394622 606 67936 N162 Y L V A K G V N P N M P D R S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3EC11 536 59969 A127 V D V N G F R A V H V A S Q Y
Baker's Yeast Sacchar. cerevisiae P39010 764 85822 S201 Y V L F N V V S K G L L D I D
Red Bread Mold Neurospora crassa Q7S3M5 729 80066 P169 L L L H Q G I P V D V E D A Y
Conservation
Percent
Protein Identity: 100 99 92.9 84.5 N.A. 91.1 90.3 N.A. 70.2 48.3 N.A. 49.6 N.A. 36.8 37.6 N.A. N.A.
Protein Similarity: 100 99.5 95.6 88.7 N.A. 96.3 96.3 N.A. 79.9 66.7 N.A. 66 N.A. 55.5 54.3 N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 100 93.3 N.A. 33.3 66.6 N.A. 53.3 N.A. 33.3 46.6 N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 100 93.3 N.A. 53.3 80 N.A. 86.6 N.A. 53.3 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.9 24 25.1
Protein Similarity: N.A. N.A. N.A. 41.3 41.3 40.8
P-Site Identity: N.A. N.A. N.A. 6.6 20 26.6
P-Site Similarity: N.A. N.A. N.A. 46.6 53.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 29 0 0 8 8 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 15 0 36 0 0 86 0 15 % D
% Glu: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % E
% Phe: 8 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 79 0 0 0 8 0 0 8 8 8 % G
% His: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 65 0 0 0 8 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 0 0 79 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 72 15 0 0 0 0 0 0 0 22 15 0 15 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 58 8 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 8 0 50 0 0 0 0 58 % N
% Pro: 0 0 0 8 0 0 0 8 15 0 0 15 0 0 0 % P
% Gln: 0 0 0 0 8 0 58 0 0 0 8 8 0 15 0 % Q
% Arg: 0 0 0 0 0 8 8 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 0 43 0 0 0 50 0 0 0 0 8 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 % T
% Val: 8 8 15 0 0 8 22 8 79 0 15 0 0 36 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 79 8 0 0 0 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _