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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC13 All Species: 27.88
Human Site: T500 Identified Species: 47.18
UniProt: Q8IUH4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUH4 NP_001001483.1 622 70861 T500 L S S H C A T T F K E D G L W
Chimpanzee Pan troglodytes XP_508324 622 70862 T500 W S S H C A T T F K E D G L W
Rhesus Macaque Macaca mulatta XP_001096184 618 70464 T496 W S N H C A T T F K E D G L W
Dog Lupus familis XP_854853 673 77171 T551 W S N H C T T T F R E D G L W
Cat Felis silvestris
Mouse Mus musculus Q9CWU2 622 70871 T500 W S N H C A T T F K E D G L W
Rat Rattus norvegicus NP_001034126 622 70868 T500 W S N H C A T T F K E D G L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506180 611 68870 T489 W S N H C A T T Y K Q D G V W
Chicken Gallus gallus NP_001025916 622 71511 S501 W G F H C E T S Y A K D G F W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001918491 645 71421 H523 W S R H C P L H Y S E E G I W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648824 637 71280 R504 Y V N Q C N V R F D D F L G A
Honey Bee Apis mellifera XP_394622 606 67936 N486 W Q F E C W T N L T N G H S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3EC11 536 59969 R429 G G T T A V Q R L W R G I P Q
Baker's Yeast Sacchar. cerevisiae P39010 764 85822 H544 F D E L E D A H E D T S Q K N
Red Bread Mold Neurospora crassa Q7S3M5 729 80066 A514 L S T L S E T A S D E C N I L
Conservation
Percent
Protein Identity: 100 99 92.9 84.5 N.A. 91.1 90.3 N.A. 70.2 48.3 N.A. 49.6 N.A. 36.8 37.6 N.A. N.A.
Protein Similarity: 100 99.5 95.6 88.7 N.A. 96.3 96.3 N.A. 79.9 66.7 N.A. 66 N.A. 55.5 54.3 N.A. N.A.
P-Site Identity: 100 93.3 86.6 73.3 N.A. 86.6 86.6 N.A. 66.6 40 N.A. 40 N.A. 13.3 13.3 N.A. N.A.
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 93.3 93.3 N.A. 93.3 60 N.A. 60 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.9 24 25.1
Protein Similarity: N.A. N.A. N.A. 41.3 41.3 40.8
P-Site Identity: N.A. N.A. N.A. 0 0 26.6
P-Site Similarity: N.A. N.A. N.A. 6.6 0 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 43 8 8 0 8 0 0 0 0 15 % A
% Cys: 0 0 0 0 79 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 0 22 8 58 0 0 0 % D
% Glu: 0 0 8 8 8 15 0 0 8 0 58 8 0 0 0 % E
% Phe: 8 0 15 0 0 0 0 0 50 0 0 8 0 8 0 % F
% Gly: 8 15 0 0 0 0 0 0 0 0 0 15 65 8 0 % G
% His: 0 0 0 65 0 0 0 15 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 15 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 43 8 0 0 8 0 % K
% Leu: 15 0 0 15 0 0 8 0 15 0 0 0 8 43 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 43 0 0 8 0 8 0 0 8 0 8 0 8 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 0 8 0 0 8 0 0 0 8 0 8 0 8 % Q
% Arg: 0 0 8 0 0 0 0 15 0 8 8 0 0 0 0 % R
% Ser: 0 65 15 0 8 0 0 8 8 8 0 8 0 8 0 % S
% Thr: 0 0 15 8 0 8 72 50 0 8 8 0 0 0 0 % T
% Val: 0 8 0 0 0 8 8 0 0 0 0 0 0 8 0 % V
% Trp: 65 0 0 0 0 8 0 0 0 8 0 0 0 0 65 % W
% Tyr: 8 0 0 0 0 0 0 0 22 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _