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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC17 All Species: 34.55
Human Site: S290 Identified Species: 58.46
UniProt: Q8IUH5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUH5 NP_056151.2 632 72640 S290 A K G Y D N P S F L R K L K A
Chimpanzee Pan troglodytes XP_509231 763 86783 S421 A K G Y D N P S F L R K L K A
Rhesus Macaque Macaca mulatta XP_001082309 771 87406 S429 A K G Y D N P S F L R K L K A
Dog Lupus familis XP_539691 637 73083 S295 A K G Y D N P S F L R K L K A
Cat Felis silvestris
Mouse Mus musculus Q80TN5 632 72602 S290 A K G Y D N P S F L R K L K A
Rat Rattus norvegicus NP_001034429 622 71347 S280 A K G Y D N P S F L R K L K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505774 298 35242
Chicken Gallus gallus NP_001025916 622 71511 S280 A K G Y D S P S F L R K L K A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121854 620 71330 S278 A K G Y D S P S Y L K R L K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648824 637 71280 S286 Q Q R R S L L S K L R H D K R
Honey Bee Apis mellifera XP_394622 606 67936 T271 E K Q G R T R T W C R D K R M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3EC11 536 59969 L241 S D K G H R Q L A L F L S K A
Baker's Yeast Sacchar. cerevisiae P39010 764 85822 G309 H S G F D Y H G Y P I K K W F
Red Bread Mold Neurospora crassa Q7S3M5 729 80066 F298 S F M T K F T F L W P F V M V
Conservation
Percent
Protein Identity: 100 82.8 81.9 94.8 N.A. 98.5 96.9 N.A. 46.5 94.9 N.A. 88.2 N.A. 46.4 46.8 N.A. N.A.
Protein Similarity: 100 82.8 81.9 95.7 N.A. 99.6 97.7 N.A. 46.9 96.5 N.A. 93.5 N.A. 63.1 62.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 93.3 N.A. 66.6 N.A. 26.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 100 N.A. 93.3 N.A. 33.3 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25.1 25.5 25.9
Protein Similarity: N.A. N.A. N.A. 40.8 42.2 43.2
P-Site Identity: N.A. N.A. N.A. 20 20 0
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 0 0 0 0 0 0 8 0 0 0 0 0 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 65 0 0 0 0 0 0 8 8 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 8 0 8 0 8 50 0 8 8 0 0 8 % F
% Gly: 0 0 65 15 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 8 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 65 8 0 8 0 0 0 8 0 8 58 15 72 0 % K
% Leu: 0 0 0 0 0 8 8 8 8 72 0 8 58 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 15 % M
% Asn: 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 58 0 0 8 8 0 0 0 0 % P
% Gln: 8 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 8 8 8 8 0 0 0 65 8 0 8 8 % R
% Ser: 15 8 0 0 8 15 0 65 0 0 0 0 8 0 0 % S
% Thr: 0 0 0 8 0 8 8 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 8 8 0 0 0 8 0 % W
% Tyr: 0 0 0 58 0 8 0 0 15 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _