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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC17 All Species: 18.18
Human Site: Y199 Identified Species: 30.77
UniProt: Q8IUH5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUH5 NP_056151.2 632 72640 Y199 T P L M W A A Y R T H S V D P
Chimpanzee Pan troglodytes XP_509231 763 86783 Y330 T P L M W A A Y R T H S V D P
Rhesus Macaque Macaca mulatta XP_001082309 771 87406 Y338 T P L M W A A Y R T H S V D P
Dog Lupus familis XP_539691 637 73083 Y204 T P L M W A A Y R T H S V D P
Cat Felis silvestris
Mouse Mus musculus Q80TN5 632 72602 Y199 T P L M W A A Y R T H S V D P
Rat Rattus norvegicus NP_001034429 622 71347 L200 S V D P T R L L L T F N V S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505774 298 35242
Chicken Gallus gallus NP_001025916 622 71511 L200 S V D P T R L L L T F N V S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121854 620 71330 L198 S V D P T R L L L T F N V S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648824 637 71280 D209 G A N P A M V D Y T H G N T A
Honey Bee Apis mellifera XP_394622 606 67936 G194 T R L L L T L G A S H S L A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q3EC11 536 59969 W164 E G R S P L H W A A Y N G F T
Baker's Yeast Sacchar. cerevisiae P39010 764 85822 A221 G R T S L L W A A Y Q G D S L
Red Bread Mold Neurospora crassa Q7S3M5 729 80066 L218 F T A L H W A L V K G S P G C
Conservation
Percent
Protein Identity: 100 82.8 81.9 94.8 N.A. 98.5 96.9 N.A. 46.5 94.9 N.A. 88.2 N.A. 46.4 46.8 N.A. N.A.
Protein Similarity: 100 82.8 81.9 95.7 N.A. 99.6 97.7 N.A. 46.9 96.5 N.A. 93.5 N.A. 63.1 62.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 0 13.3 N.A. 13.3 N.A. 13.3 26.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 0 26.6 N.A. 26.6 N.A. 13.3 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 25.1 25.5 25.9
Protein Similarity: N.A. N.A. N.A. 40.8 42.2 43.2
P-Site Identity: N.A. N.A. N.A. 0 0 13.3
P-Site Similarity: N.A. N.A. N.A. 20 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 36 43 8 22 8 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 0 22 0 0 0 0 8 0 0 0 0 8 36 8 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 22 0 0 8 0 % F
% Gly: 15 8 0 0 0 0 0 8 0 0 8 15 8 8 0 % G
% His: 0 0 0 0 8 0 8 0 0 0 50 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 0 0 43 15 15 15 29 29 22 0 0 0 8 0 8 % L
% Met: 0 0 0 36 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 29 8 0 0 % N
% Pro: 0 36 0 29 8 0 0 0 0 0 0 0 8 0 36 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 15 8 0 0 22 0 0 36 0 0 0 0 0 0 % R
% Ser: 22 0 0 15 0 0 0 0 0 8 0 50 0 29 0 % S
% Thr: 43 8 8 0 22 8 0 0 0 65 0 0 0 8 8 % T
% Val: 0 22 0 0 0 0 8 0 8 0 0 0 58 0 22 % V
% Trp: 0 0 0 0 36 8 8 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 36 8 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _