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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRLF3
All Species:
13.64
Human Site:
Y343
Identified Species:
42.86
UniProt:
Q8IUI8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUI8
NP_057070.3
442
49766
Y343
C
A
E
K
Q
D
G
Y
D
S
L
Q
R
D
Q
Chimpanzee
Pan troglodytes
XP_001152329
208
23533
A110
V
D
V
P
C
L
S
A
Q
L
D
E
S
I
L
Rhesus Macaque
Macaca mulatta
XP_001112406
442
49776
Y343
C
A
E
K
Q
D
G
Y
D
S
L
Q
R
D
Q
Dog
Lupus familis
XP_548277
571
63707
Y472
C
A
E
K
Q
N
G
Y
D
S
L
Q
R
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2L7
442
49540
Y343
C
A
E
R
Q
N
G
Y
E
S
L
Q
R
D
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511274
442
49345
H344
C
V
E
Q
Q
N
G
H
D
S
L
Q
R
D
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZX59
436
48919
C338
V
C
V
E
Q
F
D
C
E
S
L
Q
R
D
K
Zebra Danio
Brachydanio rerio
Q568M3
444
49249
R339
L
G
V
C
A
D
S
R
T
D
T
D
S
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.4
99.5
74.6
N.A.
92.9
N.A.
N.A.
86.4
N.A.
70.1
66.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.1
99.7
76.8
N.A.
98.1
N.A.
N.A.
92.7
N.A.
81.9
82.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
80
N.A.
N.A.
73.3
N.A.
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
N.A.
N.A.
93.3
N.A.
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
13
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
63
13
0
13
13
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
38
13
0
50
13
13
13
0
75
0
% D
% Glu:
0
0
63
13
0
0
0
0
25
0
0
13
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
63
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% I
% Lys:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
13
% K
% Leu:
13
0
0
0
0
13
0
0
0
13
75
0
0
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
38
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
75
0
0
0
13
0
0
75
0
0
75
% Q
% Arg:
0
0
0
13
0
0
0
13
0
0
0
0
75
0
0
% R
% Ser:
0
0
0
0
0
0
25
0
0
75
0
0
25
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% T
% Val:
25
13
38
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _