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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLVS1
All Species:
23.64
Human Site:
S212
Identified Species:
47.27
UniProt:
Q8IUQ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUQ0
NP_775790.1
354
40788
S212
A
I
E
G
L
Q
D
S
F
P
A
R
F
G
G
Chimpanzee
Pan troglodytes
XP_001158960
304
35294
W164
G
F
I
L
I
I
D
W
S
N
F
S
F
K
Q
Rhesus Macaque
Macaca mulatta
XP_001091304
354
40742
S212
A
I
E
G
L
Q
D
S
F
P
A
R
F
G
G
Dog
Lupus familis
XP_544098
354
40730
S212
A
I
E
G
L
Q
D
S
F
P
A
R
F
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4C9
354
40595
S212
A
I
E
G
L
Q
D
S
F
P
A
R
F
G
G
Rat
Rattus norvegicus
P41034
278
31827
I138
D
V
F
R
V
S
L
I
T
S
E
L
I
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513318
344
39097
S201
I
L
R
A
I
L
L
S
L
E
V
L
I
E
D
Chicken
Gallus gallus
XP_419223
332
38227
S190
A
I
E
G
L
Q
D
S
F
P
A
R
F
G
G
Frog
Xenopus laevis
Q5M7E1
332
38511
S190
A
I
E
G
L
Q
D
S
F
P
A
R
F
G
G
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
A183
T
P
S
M
L
R
L
A
I
E
G
L
Q
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396934
371
41463
R199
L
I
A
A
L
R
G
R
F
P
A
R
F
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCU1
409
46492
E228
L
F
Q
D
N
Y
P
E
L
V
A
T
K
I
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
99.7
98.8
N.A.
97.1
27.3
N.A.
62.7
88.6
84.4
74.5
N.A.
N.A.
32
N.A.
N.A.
Protein Similarity:
100
85.8
100
99.1
N.A.
98.3
44.9
N.A.
68.3
90.6
88.6
82.1
N.A.
N.A.
52.5
N.A.
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
0
N.A.
6.6
100
100
6.6
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
20
100
100
20
N.A.
N.A.
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
9
17
0
0
0
9
0
0
67
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
59
0
0
0
0
0
0
9
9
% D
% Glu:
0
0
50
0
0
0
0
9
0
17
9
0
0
9
0
% E
% Phe:
0
17
9
0
0
0
0
0
59
0
9
0
67
0
9
% F
% Gly:
9
0
0
50
0
0
9
0
0
0
9
0
0
50
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
59
9
0
17
9
0
9
9
0
0
0
17
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
17
0
% K
% Leu:
17
9
0
9
67
9
25
0
17
0
0
25
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
9
0
0
59
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
50
0
0
0
0
0
0
9
0
17
% Q
% Arg:
0
0
9
9
0
17
0
9
0
0
0
59
0
0
0
% R
% Ser:
0
0
9
0
0
9
0
59
9
9
0
9
0
0
9
% S
% Thr:
9
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% T
% Val:
0
9
0
0
9
0
0
0
0
9
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _