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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAH1
All Species:
30.61
Human Site:
Y100
Identified Species:
56.11
UniProt:
Q8IUQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUQ4
NP_001006611.1
282
31123
Y100
S
V
L
F
P
C
K
Y
A
S
S
G
C
E
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001083570
277
31013
L98
F
P
C
R
Y
A
C
L
G
C
E
I
T
L
P
Dog
Lupus familis
XP_544419
313
34552
Y131
S
V
L
F
P
C
K
Y
A
S
S
G
C
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q06985
282
31103
Y100
S
V
L
F
P
C
K
Y
S
A
S
G
C
E
I
Rat
Rattus norvegicus
Q920M9
282
31118
Y100
S
V
L
F
P
C
K
Y
A
S
S
G
C
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507643
433
47638
Y251
S
V
L
F
P
C
K
Y
A
S
S
G
C
E
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9I8X5
313
34081
Y129
A
V
L
F
P
C
K
Y
A
S
T
G
C
S
L
Zebra Danio
Brachydanio rerio
Q7ZVG6
282
31061
Y100
S
V
L
F
P
C
K
Y
A
S
S
G
C
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21461
314
33689
H132
N
V
K
F
P
C
K
H
S
G
Y
G
C
T
A
Honey Bee
Apis mellifera
XP_394284
279
30558
S100
F
P
C
K
Y
S
T
S
G
C
T
V
S
L
V
Nematode Worm
Caenorhab. elegans
Q965X6
339
37641
F149
T
V
R
F
P
C
K
F
S
T
S
G
C
P
L
Sea Urchin
Strong. purpuratus
XP_797311
281
31248
A100
V
M
F
P
C
R
Y
A
S
S
G
C
V
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93748
305
34539
Y117
S
L
E
V
P
C
R
Y
Q
N
L
G
C
Q
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
69.8
89.7
N.A.
97.1
99.6
N.A.
64.9
N.A.
71.5
97.5
N.A.
70.3
80.5
58.7
82.2
Protein Similarity:
100
N.A.
80.1
89.7
N.A.
98.9
100
N.A.
64.9
N.A.
79.5
99.6
N.A.
77
89
68.7
87.5
P-Site Identity:
100
N.A.
0
100
N.A.
86.6
100
N.A.
100
N.A.
73.3
93.3
N.A.
46.6
0
53.3
6.6
P-Site Similarity:
100
N.A.
0
100
N.A.
100
100
N.A.
100
N.A.
93.3
100
N.A.
66.6
13.3
86.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
8
47
8
0
0
0
8
8
% A
% Cys:
0
0
16
0
8
77
8
0
0
16
0
8
77
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
8
0
0
47
0
% E
% Phe:
16
0
8
70
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
8
8
77
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
39
% I
% Lys:
0
0
8
8
0
0
70
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
54
0
0
0
0
8
0
0
8
0
0
16
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
16
0
8
77
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
8
8
0
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
54
0
0
0
0
8
0
8
31
54
54
0
8
8
0
% S
% Thr:
8
0
0
0
0
0
8
0
0
8
16
0
8
8
8
% T
% Val:
8
70
0
8
0
0
0
0
0
0
0
8
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
16
0
8
62
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _