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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
12.73
Human Site:
S136
Identified Species:
25.45
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
S136
L
S
N
K
Q
D
K
S
S
N
G
A
L
C
P
Chimpanzee
Pan troglodytes
XP_520818
882
98885
S244
L
S
N
K
Q
D
K
S
S
N
G
A
L
C
P
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
S406
L
S
N
K
E
D
K
S
S
N
G
A
L
C
P
Dog
Lupus familis
XP_543747
865
97589
S227
L
S
H
K
Q
E
K
S
S
N
G
V
I
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
L243
P
S
H
K
Q
D
K
L
S
N
G
A
V
C
Q
Rat
Rattus norvegicus
XP_342789
942
106226
L243
P
S
H
K
Q
D
K
L
S
N
G
A
I
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
L250
L
S
C
N
G
L
K
L
R
N
G
G
T
H
T
Frog
Xenopus laevis
Q6DCD5
836
94386
Q211
F
H
K
L
K
M
N
Q
I
I
S
V
V
F
K
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
L241
L
C
R
K
P
L
I
L
H
L
S
R
S
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
H266
V
H
Q
L
R
P
L
H
L
C
H
F
V
L
R
Honey Bee
Apis mellifera
XP_393964
996
112258
D214
V
Q
K
I
R
A
V
D
I
F
L
T
L
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
100
93.3
60
N.A.
66.6
66.6
N.A.
N.A.
33.3
0
13.3
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
N.A.
33.3
13.3
13.3
N.A.
20
20
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
42
0
0
9
% A
% Cys:
0
9
9
0
0
0
0
0
0
9
0
0
0
42
0
% C
% Asp:
0
0
0
0
0
42
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
9
0
9
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
59
9
0
0
0
% G
% His:
0
17
25
0
0
0
0
9
9
0
9
0
0
17
0
% H
% Ile:
0
0
0
9
0
0
9
0
17
9
0
0
17
0
0
% I
% Lys:
0
0
17
59
9
0
59
0
0
0
0
0
0
9
9
% K
% Leu:
50
0
0
17
0
17
9
34
9
9
9
0
34
9
9
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
25
9
0
0
9
0
0
59
0
0
0
0
0
% N
% Pro:
17
0
0
0
9
9
0
0
0
0
0
0
0
0
25
% P
% Gln:
0
9
9
0
42
0
0
9
0
0
0
0
0
0
25
% Q
% Arg:
0
0
9
0
17
0
0
0
9
0
0
9
0
9
9
% R
% Ser:
0
59
0
0
0
0
0
34
50
0
17
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
9
% T
% Val:
17
0
0
0
0
0
9
0
0
0
0
17
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _