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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
21.82
Human Site:
S151
Identified Species:
43.64
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
S151
R
S
P
Q
Q
P
G
S
P
Q
P
S
S
L
P
Chimpanzee
Pan troglodytes
XP_520818
882
98885
S259
R
S
P
Q
Q
P
R
S
P
Q
P
S
S
L
P
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
S421
C
S
P
Q
Q
P
G
S
P
Q
P
S
S
L
P
Dog
Lupus familis
XP_543747
865
97589
S242
R
S
P
Q
Q
P
G
S
P
Q
P
P
S
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
S258
H
S
S
G
Q
P
G
S
P
Q
P
S
S
Q
Q
Rat
Rattus norvegicus
XP_342789
942
106226
S258
H
S
P
R
Q
P
G
S
P
Q
P
S
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
A265
R
P
V
R
H
P
A
A
S
L
P
A
S
L
P
Frog
Xenopus laevis
Q6DCD5
836
94386
F226
E
K
N
V
S
F
F
F
S
V
G
L
L
F
A
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
S256
K
E
L
G
R
I
S
S
P
F
V
K
R
A
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
Q281
L
F
D
E
R
T
E
Q
Q
S
P
K
L
A
N
Honey Bee
Apis mellifera
XP_393964
996
112258
S229
A
F
G
G
K
K
I
S
L
T
W
S
S
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
L22
L
W
M
L
N
G
H
L
P
H
F
S
E
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
93.3
93.3
93.3
N.A.
66.6
73.3
N.A.
N.A.
40
0
13.3
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
66.6
80
N.A.
N.A.
60
0
26.6
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
9
0
0
0
9
0
17
9
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
9
9
0
9
0
0
9
0
0
0
0
0
9
17
0
% E
% Phe:
0
17
0
0
0
9
9
9
0
9
9
0
0
9
0
% F
% Gly:
0
0
9
25
0
9
42
0
0
0
9
0
0
0
9
% G
% His:
17
0
0
0
9
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
9
9
0
0
0
0
0
17
0
0
0
% K
% Leu:
17
0
9
9
0
0
0
9
9
9
0
9
17
42
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
42
0
0
59
0
0
67
0
67
9
0
0
42
% P
% Gln:
0
0
0
34
50
0
0
9
9
50
0
0
0
17
17
% Q
% Arg:
34
0
0
17
17
0
9
0
0
0
0
0
9
0
0
% R
% Ser:
0
50
9
0
9
0
9
67
17
9
0
59
67
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
9
9
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _