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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMTC1 All Species: 21.82
Human Site: S151 Identified Species: 43.64
UniProt: Q8IUR5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUR5 NP_787057.2 774 87338 S151 R S P Q Q P G S P Q P S S L P
Chimpanzee Pan troglodytes XP_520818 882 98885 S259 R S P Q Q P R S P Q P S S L P
Rhesus Macaque Macaca mulatta XP_001101625 1044 115045 S421 C S P Q Q P G S P Q P S S L P
Dog Lupus familis XP_543747 865 97589 S242 R S P Q Q P G S P Q P P S L P
Cat Felis silvestris
Mouse Mus musculus Q3UV71 942 105796 S258 H S S G Q P G S P Q P S S Q Q
Rat Rattus norvegicus XP_342789 942 106226 S258 H S P R Q P G S P Q P S S Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416374 944 106377 A265 R P V R H P A A S L P A S L P
Frog Xenopus laevis Q6DCD5 836 94386 F226 E K N V S F F F S V G L L F A
Zebra Danio Brachydanio rerio XP_001922025 866 97506 S256 K E L G R I S S P F V K R A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K4B6 926 105342 Q281 L F D E R T E Q Q S P K L A N
Honey Bee Apis mellifera XP_393964 996 112258 S229 A F G G K K I S L T W S S E G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788690 569 64719 L22 L W M L N G H L P H F S E E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.4 73.1 83.6 N.A. 73 72.8 N.A. N.A. 66.3 23.3 52.4 N.A. 26.8 24.1 N.A. 33.4
Protein Similarity: 100 87.4 73.4 86.2 N.A. 78 78 N.A. N.A. 72.9 41 66.1 N.A. 44.1 39.5 N.A. 48
P-Site Identity: 100 93.3 93.3 93.3 N.A. 66.6 73.3 N.A. N.A. 40 0 13.3 N.A. 6.6 20 N.A. 13.3
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 66.6 80 N.A. N.A. 60 0 26.6 N.A. 20 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 9 9 0 0 0 9 0 17 9 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % D
% Glu: 9 9 0 9 0 0 9 0 0 0 0 0 9 17 0 % E
% Phe: 0 17 0 0 0 9 9 9 0 9 9 0 0 9 0 % F
% Gly: 0 0 9 25 0 9 42 0 0 0 9 0 0 0 9 % G
% His: 17 0 0 0 9 0 9 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 0 0 9 9 0 0 0 0 0 17 0 0 0 % K
% Leu: 17 0 9 9 0 0 0 9 9 9 0 9 17 42 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 9 42 0 0 59 0 0 67 0 67 9 0 0 42 % P
% Gln: 0 0 0 34 50 0 0 9 9 50 0 0 0 17 17 % Q
% Arg: 34 0 0 17 17 0 9 0 0 0 0 0 9 0 0 % R
% Ser: 0 50 9 0 9 0 9 67 17 9 0 59 67 0 0 % S
% Thr: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % T
% Val: 0 0 9 9 0 0 0 0 0 9 9 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _