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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
23.03
Human Site:
S156
Identified Species:
46.06
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
S156
P
G
S
P
Q
P
S
S
L
P
G
H
P
H
R
Chimpanzee
Pan troglodytes
XP_520818
882
98885
S264
P
R
S
P
Q
P
S
S
L
P
G
H
P
H
R
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
S426
P
G
S
P
Q
P
S
S
L
P
G
H
P
H
R
Dog
Lupus familis
XP_543747
865
97589
S247
P
G
S
P
Q
P
P
S
L
P
T
H
P
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
S263
P
G
S
P
Q
P
S
S
Q
Q
A
H
P
H
R
Rat
Rattus norvegicus
XP_342789
942
106226
S263
P
G
S
P
Q
P
S
S
Q
Q
A
H
P
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
S270
P
A
A
S
L
P
A
S
L
P
V
Q
S
R
E
Frog
Xenopus laevis
Q6DCD5
836
94386
L231
F
F
F
S
V
G
L
L
F
A
W
G
V
I
L
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
R261
I
S
S
P
F
V
K
R
A
C
V
V
S
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
L286
T
E
Q
Q
S
P
K
L
A
N
P
S
G
I
R
Honey Bee
Apis mellifera
XP_393964
996
112258
S234
K
I
S
L
T
W
S
S
E
G
T
K
R
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
E27
G
H
L
P
H
F
S
E
E
D
N
P
A
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
93.3
100
86.6
N.A.
80
80
N.A.
N.A.
33.3
0
13.3
N.A.
13.3
20
N.A.
13.3
P-Site Similarity:
100
93.3
100
86.6
N.A.
80
80
N.A.
N.A.
46.6
0
13.3
N.A.
13.3
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
9
0
17
9
17
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
9
17
0
0
0
0
0
9
% E
% Phe:
9
9
9
0
9
9
0
0
9
0
0
0
0
0
9
% F
% Gly:
9
42
0
0
0
9
0
0
0
9
25
9
9
0
0
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
50
0
50
9
% H
% Ile:
9
9
0
0
0
0
0
0
0
0
0
0
0
17
0
% I
% Lys:
9
0
0
0
0
0
17
0
0
0
0
9
0
0
0
% K
% Leu:
0
0
9
9
9
0
9
17
42
0
0
0
0
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
59
0
0
67
0
67
9
0
0
42
9
9
50
0
0
% P
% Gln:
0
0
9
9
50
0
0
0
17
17
0
9
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
0
0
9
9
59
% R
% Ser:
0
9
67
17
9
0
59
67
0
0
0
9
17
9
0
% S
% Thr:
9
0
0
0
9
0
0
0
0
0
17
0
0
0
9
% T
% Val:
0
0
0
0
9
9
0
0
0
0
17
9
9
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _