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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
14.85
Human Site:
S191
Identified Species:
29.7
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
S191
L
P
P
E
P
K
S
S
G
F
P
V
S
P
R
Chimpanzee
Pan troglodytes
XP_520818
882
98885
S299
L
P
P
E
P
K
S
S
G
F
P
V
S
P
R
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
S461
L
P
P
E
P
K
S
S
G
F
P
V
S
P
R
Dog
Lupus familis
XP_543747
865
97589
S282
S
P
P
E
P
K
S
S
G
F
P
G
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
E359
G
T
M
P
L
F
S
E
Q
D
N
P
A
S
F
Rat
Rattus norvegicus
XP_342789
942
106226
E359
G
T
M
P
L
F
S
E
Q
D
N
P
A
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
E362
G
S
M
P
M
F
S
E
Q
D
N
P
A
S
F
Frog
Xenopus laevis
Q6DCD5
836
94386
N255
N
T
P
P
S
F
S
N
S
D
N
P
A
A
D
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
E289
G
S
M
P
L
F
S
E
Q
D
N
P
A
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
T330
G
S
Q
L
P
I
F
T
R
F
D
N
P
A
S
Honey Bee
Apis mellifera
XP_393964
996
112258
T266
G
S
K
L
P
V
F
T
R
F
D
N
P
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
F51
T
Y
S
Y
L
V
A
F
N
I
W
L
L
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
100
100
86.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
13.3
13.3
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
N.A.
13.3
26.6
13.3
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
0
0
42
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
42
17
0
0
0
9
% D
% Glu:
0
0
0
34
0
0
0
34
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
42
17
9
0
50
0
0
0
0
34
% F
% Gly:
50
0
0
0
0
0
0
0
34
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
34
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
0
0
17
34
0
0
0
0
0
0
9
9
9
0
% L
% Met:
0
0
34
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
9
0
42
17
0
0
0
% N
% Pro:
0
34
42
42
50
0
0
0
0
0
34
42
17
34
0
% P
% Gln:
0
0
9
0
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
34
% R
% Ser:
9
34
9
0
9
0
75
34
9
0
0
0
34
34
17
% S
% Thr:
9
25
0
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
17
0
0
0
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _