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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
31.52
Human Site:
T370
Identified Species:
63.03
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
T370
L
F
R
S
G
V
Q
T
L
P
H
N
A
K
V
Chimpanzee
Pan troglodytes
XP_520818
882
98885
T478
L
F
R
S
G
V
Q
T
L
P
H
N
A
K
V
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
T640
L
F
R
S
G
V
Q
T
L
P
H
N
A
K
V
Dog
Lupus familis
XP_543747
865
97589
T461
L
F
R
S
G
V
Q
T
L
P
H
N
A
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
T538
L
F
R
S
G
V
Q
T
L
P
H
N
A
K
V
Rat
Rattus norvegicus
XP_342789
942
106226
T538
L
F
R
S
G
V
Q
T
L
P
H
N
A
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
T540
L
F
S
S
G
V
R
T
L
P
H
N
A
K
V
Frog
Xenopus laevis
Q6DCD5
836
94386
M429
R
V
L
Y
I
P
S
M
G
F
C
L
L
V
T
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
T468
L
F
R
S
G
I
Q
T
L
P
H
N
A
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
V509
L
F
M
S
G
V
H
V
N
Q
R
N
A
K
L
Honey Bee
Apis mellifera
XP_393964
996
112258
V442
I
F
M
S
G
L
K
V
N
D
R
N
A
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
M214
T
L
P
H
N
A
K
M
H
Y
N
Y
G
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
86.6
0
93.3
N.A.
53.3
40
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
0
100
N.A.
60
66.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
84
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
84
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
84
0
0
0
9
0
0
0
9
0
0
% G
% His:
0
0
0
9
0
0
9
0
9
0
67
0
0
0
0
% H
% Ile:
9
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
0
0
0
0
84
0
% K
% Leu:
75
9
9
0
0
9
0
0
67
0
0
9
9
0
17
% L
% Met:
0
0
17
0
0
0
0
17
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
17
0
9
84
0
9
0
% N
% Pro:
0
0
9
0
0
9
0
0
0
67
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
59
0
0
9
0
0
0
0
0
% Q
% Arg:
9
0
59
0
0
0
9
0
0
0
17
0
0
0
0
% R
% Ser:
0
0
9
84
0
0
9
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
67
0
0
0
0
0
0
9
% T
% Val:
0
9
0
0
0
67
0
17
0
0
0
0
0
9
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
9
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _