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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMTC1 All Species: 31.82
Human Site: Y738 Identified Species: 63.64
UniProt: Q8IUR5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUR5 NP_787057.2 774 87338 Y738 Y V S A R A Y Y E R A L Q L V
Chimpanzee Pan troglodytes XP_520818 882 98885 Y846 Y V S A R A Y Y E R A L Q L V
Rhesus Macaque Macaca mulatta XP_001101625 1044 115045 Y1008 Y V S A R A Y Y E R A L Q L V
Dog Lupus familis XP_543747 865 97589 Y829 Y V S A R A Y Y E R A L Q L V
Cat Felis silvestris
Mouse Mus musculus Q3UV71 942 105796 Y906 Y V S A R A Y Y E R A L K L V
Rat Rattus norvegicus XP_342789 942 106226 Y906 Y V P A R V Y Y E R A L R L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416374 944 106377 Y908 Y I T A R G Y Y E K A L Q L V
Frog Xenopus laevis Q6DCD5 836 94386 Y802 L E E A E Y N Y L R A L Q L K
Zebra Danio Brachydanio rerio XP_001922025 866 97506 Y836 Y A A A R M Y Y Q R A L L L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K4B6 926 105342 R885 H L Q I V L A R L Q K I N K L
Honey Bee Apis mellifera XP_393964 996 112258 H929 V K N T H I D H D K S S A N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788690 569 64719 K545 R A L T L D P K N E I L I E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.4 73.1 83.6 N.A. 73 72.8 N.A. N.A. 66.3 23.3 52.4 N.A. 26.8 24.1 N.A. 33.4
Protein Similarity: 100 87.4 73.4 86.2 N.A. 78 78 N.A. N.A. 72.9 41 66.1 N.A. 44.1 39.5 N.A. 48
P-Site Identity: 100 100 100 100 N.A. 93.3 80 N.A. N.A. 73.3 46.6 60 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 86.6 N.A. N.A. 93.3 46.6 73.3 N.A. 33.3 40 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 75 0 42 9 0 0 0 75 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 9 0 9 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 9 0 0 0 59 9 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 9 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 9 0 9 0 0 0 0 9 9 9 0 0 % I
% Lys: 0 9 0 0 0 0 0 9 0 17 9 0 9 9 9 % K
% Leu: 9 9 9 0 9 9 0 0 17 0 0 84 9 75 17 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 9 0 9 0 0 0 9 9 9 % N
% Pro: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 9 9 0 0 50 0 0 % Q
% Arg: 9 0 0 0 67 0 0 9 0 67 0 0 9 0 0 % R
% Ser: 0 0 42 0 0 0 0 0 0 0 9 9 0 0 9 % S
% Thr: 0 0 9 17 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 9 50 0 0 9 9 0 0 0 0 0 0 0 0 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 67 0 0 0 0 9 67 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _