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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC1
All Species:
31.82
Human Site:
Y738
Identified Species:
63.64
UniProt:
Q8IUR5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUR5
NP_787057.2
774
87338
Y738
Y
V
S
A
R
A
Y
Y
E
R
A
L
Q
L
V
Chimpanzee
Pan troglodytes
XP_520818
882
98885
Y846
Y
V
S
A
R
A
Y
Y
E
R
A
L
Q
L
V
Rhesus Macaque
Macaca mulatta
XP_001101625
1044
115045
Y1008
Y
V
S
A
R
A
Y
Y
E
R
A
L
Q
L
V
Dog
Lupus familis
XP_543747
865
97589
Y829
Y
V
S
A
R
A
Y
Y
E
R
A
L
Q
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UV71
942
105796
Y906
Y
V
S
A
R
A
Y
Y
E
R
A
L
K
L
V
Rat
Rattus norvegicus
XP_342789
942
106226
Y906
Y
V
P
A
R
V
Y
Y
E
R
A
L
R
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416374
944
106377
Y908
Y
I
T
A
R
G
Y
Y
E
K
A
L
Q
L
V
Frog
Xenopus laevis
Q6DCD5
836
94386
Y802
L
E
E
A
E
Y
N
Y
L
R
A
L
Q
L
K
Zebra Danio
Brachydanio rerio
XP_001922025
866
97506
Y836
Y
A
A
A
R
M
Y
Y
Q
R
A
L
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
R885
H
L
Q
I
V
L
A
R
L
Q
K
I
N
K
L
Honey Bee
Apis mellifera
XP_393964
996
112258
H929
V
K
N
T
H
I
D
H
D
K
S
S
A
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788690
569
64719
K545
R
A
L
T
L
D
P
K
N
E
I
L
I
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
73.1
83.6
N.A.
73
72.8
N.A.
N.A.
66.3
23.3
52.4
N.A.
26.8
24.1
N.A.
33.4
Protein Similarity:
100
87.4
73.4
86.2
N.A.
78
78
N.A.
N.A.
72.9
41
66.1
N.A.
44.1
39.5
N.A.
48
P-Site Identity:
100
100
100
100
N.A.
93.3
80
N.A.
N.A.
73.3
46.6
60
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
93.3
46.6
73.3
N.A.
33.3
40
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
75
0
42
9
0
0
0
75
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
9
0
9
0
0
0
0
0
0
% D
% Glu:
0
9
9
0
9
0
0
0
59
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
9
0
0
0
0
9
9
9
0
0
% I
% Lys:
0
9
0
0
0
0
0
9
0
17
9
0
9
9
9
% K
% Leu:
9
9
9
0
9
9
0
0
17
0
0
84
9
75
17
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
9
0
0
0
9
9
9
% N
% Pro:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
9
9
0
0
50
0
0
% Q
% Arg:
9
0
0
0
67
0
0
9
0
67
0
0
9
0
0
% R
% Ser:
0
0
42
0
0
0
0
0
0
0
9
9
0
0
9
% S
% Thr:
0
0
9
17
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
50
0
0
9
9
0
0
0
0
0
0
0
0
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
9
67
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _