KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX4
All Species:
9.09
Human Site:
T352
Identified Species:
20
UniProt:
Q8IUS5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUS5
NP_775838.3
362
42324
T352
I
V
N
K
L
I
W
T
F
L
K
E
E
T
R
Chimpanzee
Pan troglodytes
XP_001152592
362
42266
T352
I
V
N
K
L
I
W
T
F
L
K
E
E
T
R
Rhesus Macaque
Macaca mulatta
XP_001098374
362
42322
T352
I
V
N
K
L
I
W
T
F
L
K
E
E
T
R
Dog
Lupus familis
XP_547281
327
38162
F318
V
N
K
L
I
W
T
F
L
K
E
E
T
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE26
359
41487
A350
I
V
N
G
L
I
W
A
F
L
K
E
E
T
R
Rat
Rattus norvegicus
P80299
554
62322
K539
E
V
N
Q
I
L
I
K
W
L
K
T
E
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520751
203
23923
F194
V
N
K
L
I
W
T
F
L
K
E
E
T
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
I308
A
D
K
P
L
D
F
I
S
S
I
I
T
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
F333
L
A
D
E
V
G
R
F
A
C
R
H
R
I
A
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
K331
L
V
N
Q
L
M
R
K
Y
L
E
R
E
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53750
290
32738
E281
T
H
V
V
A
I
A
E
E
I
I
S
M
F
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.4
78.1
N.A.
88.4
23.1
N.A.
49.7
N.A.
N.A.
21.5
N.A.
N.A.
N.A.
20.6
39.2
Protein Similarity:
100
99.4
99.4
82
N.A.
93.9
38.9
N.A.
53.5
N.A.
N.A.
40
N.A.
N.A.
N.A.
34.3
59.3
P-Site Identity:
100
100
100
6.6
N.A.
86.6
33.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
66.6
N.A.
33.3
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
10
10
10
0
0
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
0
0
10
10
0
28
55
55
0
0
% E
% Phe:
0
0
0
0
0
0
10
28
37
0
0
0
0
19
0
% F
% Gly:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
37
0
0
0
28
46
10
10
0
10
19
10
0
28
0
% I
% Lys:
0
0
28
28
0
0
0
19
0
19
46
0
0
0
19
% K
% Leu:
19
0
0
19
55
10
0
0
19
55
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
19
55
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
19
0
0
0
10
10
10
19
37
% R
% Ser:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% S
% Thr:
10
0
0
0
0
0
19
28
0
0
0
10
28
37
10
% T
% Val:
19
55
10
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
19
37
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _