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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX4
All Species:
11.82
Human Site:
Y216
Identified Species:
26
UniProt:
Q8IUS5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUS5
NP_775838.3
362
42324
Y216
A
Q
L
L
K
S
S
Y
Y
Y
F
F
Q
I
P
Chimpanzee
Pan troglodytes
XP_001152592
362
42266
Y216
A
Q
L
L
K
S
S
Y
Y
Y
F
F
Q
I
P
Rhesus Macaque
Macaca mulatta
XP_001098374
362
42322
Y216
A
Q
L
L
K
S
S
Y
Y
Y
F
F
Q
I
P
Dog
Lupus familis
XP_547281
327
38162
P188
H
Y
Y
F
F
Q
I
P
W
F
P
E
F
M
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE26
359
41487
F214
A
Q
L
F
R
S
S
F
Y
Y
F
F
Q
I
P
Rat
Rattus norvegicus
P80299
554
62322
S400
A
E
L
E
K
N
M
S
R
T
F
K
S
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520751
203
23923
P64
Y
Y
Y
F
F
Q
M
P
W
F
P
E
F
M
F
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
F178
L
T
S
A
H
T
N
F
H
A
Y
I
Q
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
L200
E
G
S
A
M
E
A
L
G
G
M
V
H
F
L
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
H196
F
S
E
L
L
T
S
H
L
P
Q
I
I
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53750
290
32738
Y151
L
K
E
Y
W
K
S
Y
Q
S
D
P
V
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.4
78.1
N.A.
88.4
23.1
N.A.
49.7
N.A.
N.A.
21.5
N.A.
N.A.
N.A.
20.6
39.2
Protein Similarity:
100
99.4
99.4
82
N.A.
93.9
38.9
N.A.
53.5
N.A.
N.A.
40
N.A.
N.A.
N.A.
34.3
59.3
P-Site Identity:
100
100
100
0
N.A.
80
26.6
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
20
N.A.
93.3
40
N.A.
20
N.A.
N.A.
40
N.A.
N.A.
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
0
19
0
0
10
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
10
19
10
0
10
0
0
0
0
0
19
0
0
0
% E
% Phe:
10
0
0
28
19
0
0
19
0
19
46
37
19
28
28
% F
% Gly:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% G
% His:
10
0
0
0
10
0
0
10
10
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
19
10
37
0
% I
% Lys:
0
10
0
0
37
10
0
0
0
0
0
10
0
0
0
% K
% Leu:
19
0
46
37
10
0
0
10
10
0
0
0
0
0
10
% L
% Met:
0
0
0
0
10
0
19
0
0
0
10
0
0
28
10
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
19
0
10
19
10
0
0
37
% P
% Gln:
0
37
0
0
0
19
0
0
10
0
10
0
46
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
10
19
0
0
37
55
10
0
10
0
0
10
0
10
% S
% Thr:
0
10
0
0
0
19
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% V
% Trp:
0
0
0
0
10
0
0
0
19
0
0
0
0
0
0
% W
% Tyr:
10
19
19
10
0
0
0
37
37
37
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _