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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHX4
All Species:
17.27
Human Site:
Y264
Identified Species:
38
UniProt:
Q8IUS5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUS5
NP_775838.3
362
42324
Y264
T
T
E
D
L
E
A
Y
I
Y
V
F
S
Q
P
Chimpanzee
Pan troglodytes
XP_001152592
362
42266
Y264
T
T
E
D
L
E
A
Y
I
Y
V
F
S
Q
P
Rhesus Macaque
Macaca mulatta
XP_001098374
362
42322
Y264
T
T
E
D
L
E
A
Y
I
Y
V
F
S
Q
P
Dog
Lupus familis
XP_547281
327
38162
P236
Y
I
Y
V
F
S
Q
P
G
A
L
S
G
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6IE26
359
41487
Y262
T
T
E
D
L
E
A
Y
V
Y
V
F
S
Q
P
Rat
Rattus norvegicus
P80299
554
62322
Y448
T
T
E
E
E
I
E
Y
Y
I
Q
Q
F
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520751
203
23923
P112
Y
I
Y
V
F
S
Q
P
G
A
L
T
G
P
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRD9
317
34905
E226
F
L
L
T
N
L
E
E
Q
N
G
Q
Y
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9BIB3
364
40203
S248
P
S
Q
I
R
E
V
S
E
H
E
Y
T
W
R
Sea Urchin
Strong. purpuratus
XP_796464
341
39896
F244
T
D
E
D
I
Q
A
F
K
Y
S
I
S
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53750
290
32738
R199
L
D
I
A
L
I
Q
R
T
G
Q
T
D
I
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.4
78.1
N.A.
88.4
23.1
N.A.
49.7
N.A.
N.A.
21.5
N.A.
N.A.
N.A.
20.6
39.2
Protein Similarity:
100
99.4
99.4
82
N.A.
93.9
38.9
N.A.
53.5
N.A.
N.A.
40
N.A.
N.A.
N.A.
34.3
59.3
P-Site Identity:
100
100
100
0
N.A.
93.3
26.6
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
6.6
46.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
40
N.A.
6.6
N.A.
N.A.
0
N.A.
N.A.
N.A.
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
46
0
0
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
46
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
55
10
10
46
19
10
10
0
10
0
0
0
0
% E
% Phe:
10
0
0
0
19
0
0
10
0
0
0
37
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
19
10
10
0
19
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
19
10
10
10
19
0
0
28
10
0
10
0
10
19
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
19
10
% K
% Leu:
10
10
10
0
46
10
0
0
0
0
19
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
19
0
0
0
0
0
19
46
% P
% Gln:
0
0
10
0
0
10
28
0
10
0
19
19
0
37
10
% Q
% Arg:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
10
0
0
0
19
0
10
0
0
10
10
46
0
0
% S
% Thr:
55
46
0
10
0
0
0
0
10
0
0
19
10
0
0
% T
% Val:
0
0
0
19
0
0
10
0
10
0
37
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% W
% Tyr:
19
0
19
0
0
0
0
46
10
46
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _