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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPHX4 All Species: 13.33
Human Site: Y73 Identified Species: 29.33
UniProt: Q8IUS5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUS5 NP_775838.3 362 42324 Y73 P S L G T H C Y V R I K D S G
Chimpanzee Pan troglodytes XP_001152592 362 42266 Y73 S S L G T H C Y V R I K D S G
Rhesus Macaque Macaca mulatta XP_001098374 362 42322 Y73 P S L G T H C Y V R I K D S G
Dog Lupus familis XP_547281 327 38162 L62 E R G K P L M L L L H G F P E
Cat Felis silvestris
Mouse Mus musculus Q6IE26 359 41487 Y71 P S L G T H C Y V R I K D S G
Rat Rattus norvegicus P80299 554 62322 D195 S N L K P A R D M G M V T I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520751 203 23923
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DRD9 317 34905 S52 S D S M R T A S P V N L T Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9BIB3 364 40203 D71 E K K D A N I D G D V F N V Y
Sea Urchin Strong. purpuratus XP_796464 341 39896 V67 G T H K F V Q V K N L K L H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53750 290 32738 G25 K V W Y R E A G A A G N P T I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.4 78.1 N.A. 88.4 23.1 N.A. 49.7 N.A. N.A. 21.5 N.A. N.A. N.A. 20.6 39.2
Protein Similarity: 100 99.4 99.4 82 N.A. 93.9 38.9 N.A. 53.5 N.A. N.A. 40 N.A. N.A. N.A. 34.3 59.3
P-Site Identity: 100 93.3 100 0 N.A. 100 6.6 N.A. 0 N.A. N.A. 0 N.A. N.A. N.A. 0 6.6
P-Site Similarity: 100 93.3 100 6.6 N.A. 100 26.6 N.A. 0 N.A. N.A. 0 N.A. N.A. N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 32.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 19 0 10 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 0 0 0 19 0 10 0 0 37 0 10 % D
% Glu: 19 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 10 10 0 0 % F
% Gly: 10 0 10 37 0 0 0 10 10 10 10 10 0 0 37 % G
% His: 0 0 10 0 0 37 0 0 0 0 10 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 37 0 0 10 10 % I
% Lys: 10 10 10 28 0 0 0 0 10 0 0 46 0 0 0 % K
% Leu: 0 0 46 0 0 10 0 10 10 10 10 10 10 0 10 % L
% Met: 0 0 0 10 0 0 10 0 10 0 10 0 0 0 0 % M
% Asn: 0 10 0 0 0 10 0 0 0 10 10 10 10 0 0 % N
% Pro: 28 0 0 0 19 0 0 0 10 0 0 0 10 10 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 19 0 10 0 0 37 0 0 0 0 0 % R
% Ser: 28 37 10 0 0 0 0 10 0 0 0 0 0 37 0 % S
% Thr: 0 10 0 0 37 10 0 0 0 0 0 0 19 10 0 % T
% Val: 0 10 0 0 0 10 0 10 37 10 10 10 0 10 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 37 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _