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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RELL1 All Species: 31.52
Human Site: S249 Identified Species: 77.04
UniProt: Q8IUW5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUW5 NP_001078868.1 271 29340 S249 R R S L M S V S G A E T V N G
Chimpanzee Pan troglodytes XP_517142 244 26899 S222 R R S L M S V S G A E T V N G
Rhesus Macaque Macaca mulatta XP_001086170 271 29384 S249 R R S L M S V S G A E T V N G
Dog Lupus familis XP_536264 271 29247 S249 R R S L M S V S G T D S V N G
Cat Felis silvestris
Mouse Mus musculus Q8K2J7 272 29333 S250 R R S L M S V S G I E S V N G
Rat Rattus norvegicus NP_001107248 272 29517 S250 R R S L M S V S G I E S V N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513162 269 29191 S247 R R S L M S V S G G E S V N G
Chicken Gallus gallus Q5F3A4 288 31139 T251 R K S L M S V T G V E G L N G
Frog Xenopus laevis NP_001079894 223 24255 P202 N G E V P A T P V S V D T R Q
Zebra Danio Brachydanio rerio NP_996956 401 43502 S363 E A P Q P E S S D T D S M D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.6 98.8 88.9 N.A. 87.8 88.5 N.A. 73.8 60.4 40.5 25.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 90 99.6 93.3 N.A. 92.6 93.3 N.A. 84.1 72.2 52 37.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 86.6 86.6 N.A. 86.6 66.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 93.3 86.6 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 30 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 20 10 0 10 0 % D
% Glu: 10 0 10 0 0 10 0 0 0 0 70 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 80 10 0 10 0 0 80 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 80 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 0 0 0 0 80 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 80 0 % N
% Pro: 0 0 10 0 20 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 80 70 0 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 80 0 0 80 10 80 0 10 0 50 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 10 0 20 0 30 10 0 0 % T
% Val: 0 0 0 10 0 0 80 0 10 10 10 0 70 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _