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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM126B
All Species:
13.64
Human Site:
Y63
Identified Species:
33.33
UniProt:
Q8IUX1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUX1
NP_060950.2
230
25943
Y63
I
I
E
K
N
F
D
Y
L
R
K
E
M
T
Q
Chimpanzee
Pan troglodytes
XP_001175263
230
25913
Y63
I
I
E
K
K
F
D
Y
L
R
K
E
M
T
Q
Rhesus Macaque
Macaca mulatta
XP_001100016
230
25842
Y63
I
I
E
K
N
F
D
Y
L
R
K
E
M
T
P
Dog
Lupus familis
XP_542274
230
25505
Y63
I
I
E
K
K
F
E
Y
L
R
R
E
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1R1
230
25425
H63
I
I
E
K
K
F
E
H
Y
R
N
D
K
T
L
Rat
Rattus norvegicus
Q5HZA9
196
21639
Y39
L
L
E
Y
G
S
A
Y
I
G
L
N
A
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512850
372
40099
L198
I
A
R
K
I
E
L
L
P
E
L
E
R
N
L
Chicken
Gallus gallus
XP_001235495
209
23236
N52
G
S
Y
F
L
A
G
N
A
S
L
C
G
L
T
Frog
Xenopus laevis
NP_001079826
202
22332
N45
G
S
I
Y
L
G
I
N
S
A
F
A
G
L
I
Zebra Danio
Brachydanio rerio
NP_957092
201
21897
A44
S
R
G
P
L
Y
L
A
A
N
A
G
I
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
89.5
63.9
N.A.
55.2
26.9
N.A.
24.1
23.9
30.4
23.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
92.1
73.9
N.A.
71.3
43.9
N.A.
34.6
46.9
45.6
43.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
66.6
N.A.
46.6
13.3
N.A.
20
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
80
N.A.
66.6
33.3
N.A.
20
0
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
10
20
10
10
10
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
30
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
60
0
0
10
20
0
0
10
0
50
0
0
0
% E
% Phe:
0
0
0
10
0
50
0
0
0
0
10
0
0
0
10
% F
% Gly:
20
0
10
0
10
10
10
0
0
10
0
10
20
0
10
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
60
50
10
0
10
0
10
0
10
0
0
0
10
0
10
% I
% Lys:
0
0
0
60
30
0
0
0
0
0
30
0
20
0
0
% K
% Leu:
10
10
0
0
30
0
20
10
40
0
30
0
0
20
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% M
% Asn:
0
0
0
0
20
0
0
20
0
10
10
10
0
10
0
% N
% Pro:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% Q
% Arg:
0
10
10
0
0
0
0
0
0
50
10
0
10
0
0
% R
% Ser:
10
20
0
0
0
10
0
0
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
20
0
10
0
50
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _