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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EGFL6
All Species:
19.39
Human Site:
S259
Identified Species:
53.33
UniProt:
Q8IUX8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUX8
NP_056322.2
553
61317
S259
K
G
N
G
L
R
C
S
A
I
P
E
N
S
V
Chimpanzee
Pan troglodytes
XP_528894
554
61354
S259
K
G
N
G
L
R
C
S
A
I
P
E
N
S
V
Rhesus Macaque
Macaca mulatta
XP_001085018
563
61733
V254
Q
G
D
G
L
T
C
V
Y
I
P
K
V
M
I
Dog
Lupus familis
XP_548865
554
60684
S259
K
G
S
G
L
Q
C
S
V
I
P
E
N
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJZ5
550
61502
S257
R
G
N
G
L
Q
C
S
V
I
P
E
H
S
V
Rat
Rattus norvegicus
Q5Y4N8
932
102290
Q359
R
M
D
P
G
G
S
Q
A
H
G
N
F
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515269
597
65649
S303
R
G
N
G
F
E
C
S
V
I
P
E
N
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Q8AVH7
544
61030
S265
K
G
N
G
Q
E
C
S
A
V
F
N
K
P
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77469
728
79302
V280
L
F
Q
H
G
H
C
V
D
V
D
E
C
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
39.9
82.8
N.A.
77.9
21.7
N.A.
60.2
N.A.
54.9
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
100
99.4
57
89.5
N.A.
86.6
31.9
N.A.
73.3
N.A.
69.8
N.A.
N.A.
N.A.
N.A.
33.5
N.A.
P-Site Identity:
100
100
40
80
N.A.
73.3
6.6
N.A.
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
66.6
93.3
N.A.
93.3
26.6
N.A.
80
N.A.
60
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
89
0
0
0
0
0
12
0
12
% C
% Asp:
0
0
23
0
0
0
0
0
12
0
12
0
0
0
0
% D
% Glu:
0
0
0
0
0
23
0
0
0
0
0
67
0
0
0
% E
% Phe:
0
12
0
0
12
0
0
0
0
0
12
0
12
0
0
% F
% Gly:
0
78
0
78
23
12
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
12
0
12
0
0
0
12
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
12
% I
% Lys:
45
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% K
% Leu:
12
0
0
0
56
0
0
0
0
0
0
0
0
0
12
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
56
0
0
0
0
0
0
0
0
23
45
12
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
67
0
0
12
0
% P
% Gln:
12
0
12
0
12
23
0
12
0
0
0
0
0
0
0
% Q
% Arg:
34
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
0
0
0
12
67
0
0
0
0
0
56
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
23
34
23
0
0
12
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _