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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRAMD2
All Species:
6.97
Human Site:
S257
Identified Species:
17.04
UniProt:
Q8IUY3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUY3
NP_001012660.1
354
40249
S257
K
S
R
A
Q
V
A
S
E
N
G
G
R
W
A
Chimpanzee
Pan troglodytes
XP_001156709
432
47879
A300
L
N
V
S
K
G
E
A
K
P
T
R
A
D
A
Rhesus Macaque
Macaca mulatta
XP_001091654
354
39974
S257
K
S
R
T
Q
V
A
S
E
N
G
G
K
W
A
Dog
Lupus familis
XP_854022
500
55176
E399
Q
S
P
S
S
L
R
E
W
G
G
G
A
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3V3G7
320
36423
P236
I
S
C
I
S
Q
I
P
T
D
S
T
D
S
C
Rat
Rattus norvegicus
Q5FVG8
445
49211
T309
S
Q
T
V
L
N
V
T
K
G
E
T
K
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507185
450
50380
V318
E
A
Q
A
V
L
K
V
I
K
R
E
V
K
P
Chicken
Gallus gallus
XP_413709
309
34783
L225
H
R
T
S
V
S
S
L
S
A
K
E
S
F
T
Frog
Xenopus laevis
NP_001106300
337
38532
S248
L
N
I
W
K
M
L
S
M
N
A
L
L
F
I
Zebra Danio
Brachydanio rerio
XP_687453
286
32301
A202
K
P
S
V
V
S
V
A
S
S
L
P
D
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.6
93.7
56
N.A.
68
26.9
N.A.
24.6
58.7
29.1
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.2
95.7
62.4
N.A.
73.1
37.7
N.A.
38.2
66.9
48
56.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
86.6
20
N.A.
6.6
0
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
93.3
40
N.A.
13.3
20
N.A.
33.3
20
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
20
0
0
20
20
0
10
10
0
20
0
30
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
20
10
0
% D
% Glu:
10
0
0
0
0
0
10
10
20
0
10
20
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
20
30
30
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
10
0
0
10
0
10
0
0
0
0
0
10
% I
% Lys:
30
0
0
0
20
0
10
0
20
10
10
0
20
10
10
% K
% Leu:
20
0
0
0
10
20
10
10
0
0
10
10
10
10
10
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
10
0
0
0
30
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
10
0
10
0
10
0
10
20
% P
% Gln:
10
10
10
0
20
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
20
0
0
0
10
0
0
0
10
10
10
10
0
% R
% Ser:
10
40
10
30
20
20
10
30
20
10
10
0
10
10
0
% S
% Thr:
0
0
20
10
0
0
0
10
10
0
10
20
0
0
10
% T
% Val:
0
0
10
20
30
20
20
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
10
0
0
0
0
20
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _