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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L2
All Species:
52.12
Human Site:
S145
Identified Species:
76.44
UniProt:
Q8IUZ5
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUZ5
NP_699204.1
450
49711
S145
H
A
Y
H
G
H
L
S
S
L
I
D
I
S
P
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
S144
H
A
Y
H
G
H
L
S
S
L
I
E
I
S
P
Rhesus Macaque
Macaca mulatta
XP_001095786
450
49770
S145
H
A
Y
H
G
H
L
S
S
L
I
D
I
S
P
Dog
Lupus familis
XP_538569
450
49862
S145
H
A
Y
H
G
H
L
S
S
L
I
D
I
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1K4
467
51947
S145
H
A
Y
H
G
H
L
S
S
L
I
D
I
S
P
Rat
Rattus norvegicus
Q64565
512
57182
P200
G
A
Y
H
G
C
S
P
Y
T
L
G
L
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518367
451
50169
S145
H
C
Y
H
G
H
L
S
S
L
I
D
I
S
P
Chicken
Gallus gallus
XP_414688
533
59234
T227
H
A
Y
H
G
H
L
T
S
L
I
D
I
S
P
Frog
Xenopus laevis
Q6DEB1
509
56952
T144
H
A
Y
H
G
H
V
T
S
L
I
D
I
S
P
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
S145
N
A
Y
H
G
H
V
S
S
L
I
D
I
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
Q155
H
A
Y
H
G
H
L
Q
S
V
M
E
V
S
P
Honey Bee
Apis mellifera
XP_392348
482
53855
T147
H
A
Y
H
G
H
L
T
S
M
I
D
I
S
P
Nematode Worm
Caenorhab. elegans
P91408
467
51626
T163
H
A
Y
H
G
H
V
T
T
T
M
E
L
S
P
Sea Urchin
Strong. purpuratus
XP_793741
543
60687
S147
H
A
Y
H
G
H
T
S
S
V
I
D
I
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
S195
N
A
Y
H
G
G
S
S
N
T
I
G
L
T
A
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
E142
K
A
I
I
L
G
A
E
G
N
F
H
G
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.1
96.8
87.7
N.A.
83.9
31.8
N.A.
81.3
64.1
56.5
57.1
N.A.
47.3
53.3
44.1
45.6
Protein Similarity:
100
74.9
98.4
94.6
N.A.
89.9
49.6
N.A.
90.9
75
73.4
73.3
N.A.
66.5
72.6
65
62
P-Site Identity:
100
93.3
100
100
N.A.
100
26.6
N.A.
93.3
93.3
86.6
86.6
N.A.
66.6
86.6
53.3
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
93.3
100
100
100
N.A.
93.3
100
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
94
0
0
0
0
7
0
0
0
0
0
0
0
7
% A
% Cys:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
63
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
0
0
19
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
7
0
0
0
94
13
0
0
7
0
0
13
7
0
0
% G
% His:
75
0
0
94
0
82
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
7
7
0
0
0
0
0
0
75
0
69
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
7
0
57
0
0
57
7
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
13
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
0
0
7
7
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
82
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
13
57
75
0
0
0
0
82
0
% S
% Thr:
0
0
0
0
0
0
7
25
7
19
0
0
0
13
7
% T
% Val:
0
0
0
0
0
0
19
0
0
13
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
94
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _