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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L2
All Species:
27.27
Human Site:
S418
Identified Species:
40
UniProt:
Q8IUZ5
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUZ5
NP_699204.1
450
49711
S418
F
K
P
P
M
C
F
S
L
D
N
A
R
Q
V
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
T418
I
K
P
P
M
C
F
T
E
E
D
A
K
F
M
Rhesus Macaque
Macaca mulatta
XP_001095786
450
49770
S418
F
K
P
P
M
C
F
S
L
D
N
A
R
Q
V
Dog
Lupus familis
XP_538569
450
49862
S418
F
K
P
P
M
C
F
S
V
D
N
A
Q
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1K4
467
51947
N418
F
K
P
P
M
C
F
N
V
D
N
A
Q
H
V
Rat
Rattus norvegicus
Q64565
512
57182
R480
G
N
F
S
Q
T
F
R
I
A
P
P
M
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518367
451
50169
S418
F
K
P
P
M
C
F
S
T
D
D
A
K
R
V
Chicken
Gallus gallus
XP_414688
533
59234
T500
F
K
P
P
M
C
F
T
M
E
D
A
K
F
V
Frog
Xenopus laevis
Q6DEB1
509
56952
N419
F
K
P
P
M
C
F
N
K
E
D
A
K
L
V
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
S420
F
K
P
P
M
C
F
S
R
E
D
A
E
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
N432
L
K
P
P
M
C
F
N
R
E
N
A
D
E
F
Honey Bee
Apis mellifera
XP_392348
482
53855
T425
L
K
P
P
M
V
F
T
I
E
N
V
N
H
L
Nematode Worm
Caenorhab. elegans
P91408
467
51626
D431
Y
G
I
L
L
N
A
D
G
P
H
T
N
I
L
Sea Urchin
Strong. purpuratus
XP_793741
543
60687
D421
F
K
P
P
M
V
F
D
E
G
N
V
N
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
L444
I
L
V
G
K
G
G
L
H
G
N
V
F
R
I
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
L381
T
A
W
D
L
C
L
L
M
K
D
H
G
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.1
96.8
87.7
N.A.
83.9
31.8
N.A.
81.3
64.1
56.5
57.1
N.A.
47.3
53.3
44.1
45.6
Protein Similarity:
100
74.9
98.4
94.6
N.A.
89.9
49.6
N.A.
90.9
75
73.4
73.3
N.A.
66.5
72.6
65
62
P-Site Identity:
100
46.6
100
80
N.A.
73.3
13.3
N.A.
73.3
60
60
60
N.A.
53.3
40
0
46.6
P-Site Similarity:
100
80
100
93.3
N.A.
93.3
26.6
N.A.
93.3
93.3
86.6
73.3
N.A.
73.3
66.6
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
0
0
7
0
63
0
0
7
% A
% Cys:
0
0
0
0
0
69
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
13
0
32
38
0
7
7
0
% D
% Glu:
0
0
0
0
0
0
0
0
13
38
0
0
7
7
0
% E
% Phe:
57
0
7
0
0
0
82
0
0
0
0
0
7
19
7
% F
% Gly:
7
7
0
7
0
7
7
0
7
13
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
7
0
19
0
% H
% Ile:
13
0
7
0
0
0
0
0
13
0
0
0
0
7
7
% I
% Lys:
0
75
0
0
7
0
0
0
7
7
0
0
25
0
0
% K
% Leu:
13
7
0
7
13
0
7
13
13
0
0
0
0
13
25
% L
% Met:
0
0
0
0
75
0
0
0
13
0
0
0
7
0
7
% M
% Asn:
0
7
0
0
0
7
0
19
0
0
50
0
19
0
0
% N
% Pro:
0
0
75
75
0
0
0
0
0
7
7
7
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
13
13
0
% Q
% Arg:
0
0
0
0
0
0
0
7
13
0
0
0
13
19
0
% R
% Ser:
0
0
0
7
0
0
0
32
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
7
0
19
7
0
0
7
0
0
0
% T
% Val:
0
0
7
0
0
13
0
0
13
0
0
19
0
0
50
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _