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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L2
All Species:
48.79
Human Site:
T128
Identified Species:
71.56
UniProt:
Q8IUZ5
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUZ5
NP_699204.1
450
49711
T128
L
R
L
A
R
H
Y
T
G
H
Q
D
V
V
V
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
R127
L
R
L
A
R
Q
F
R
G
H
Q
D
V
I
T
Rhesus Macaque
Macaca mulatta
XP_001095786
450
49770
T128
L
R
L
A
R
H
Y
T
G
H
Q
D
V
V
V
Dog
Lupus familis
XP_538569
450
49862
T128
L
R
L
A
R
Q
Y
T
G
H
W
D
V
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1K4
467
51947
T128
L
R
L
A
R
Q
Y
T
G
H
Q
D
V
V
V
Rat
Rattus norvegicus
Q64565
512
57182
S183
M
V
M
A
R
A
Y
S
N
H
T
D
I
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518367
451
50169
T128
L
R
L
A
R
Q
Y
T
G
H
R
D
V
V
V
Chicken
Gallus gallus
XP_414688
533
59234
T210
L
R
M
A
R
Q
F
T
K
H
E
D
V
I
V
Frog
Xenopus laevis
Q6DEB1
509
56952
T127
L
R
L
A
R
Q
Y
T
G
H
Q
D
V
I
T
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
T128
L
R
L
A
W
Q
Y
T
G
H
K
D
I
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
T138
L
R
L
A
R
N
F
T
K
R
Q
D
V
I
T
Honey Bee
Apis mellifera
XP_392348
482
53855
T130
L
R
L
A
Q
T
Y
T
N
N
K
D
M
I
V
Nematode Worm
Caenorhab. elegans
P91408
467
51626
T146
L
R
L
A
R
D
Y
T
K
H
K
D
A
I
V
Sea Urchin
Strong. purpuratus
XP_793741
543
60687
T130
L
R
L
V
H
R
H
T
G
S
S
D
M
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
T178
M
M
M
A
R
L
Y
T
G
S
L
E
M
I
S
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
G125
L
K
L
A
R
R
W
G
Y
M
K
K
N
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.1
96.8
87.7
N.A.
83.9
31.8
N.A.
81.3
64.1
56.5
57.1
N.A.
47.3
53.3
44.1
45.6
Protein Similarity:
100
74.9
98.4
94.6
N.A.
89.9
49.6
N.A.
90.9
75
73.4
73.3
N.A.
66.5
72.6
65
62
P-Site Identity:
100
66.6
100
86.6
N.A.
93.3
33.3
N.A.
86.6
60
80
60
N.A.
60
53.3
66.6
46.6
P-Site Similarity:
100
80
100
86.6
N.A.
93.3
66.6
N.A.
93.3
86.6
86.6
80
N.A.
80
86.6
80
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
94
0
7
0
0
0
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
88
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
63
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
13
7
0
0
69
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
13
63
7
% I
% Lys:
0
7
0
0
0
0
0
0
19
0
25
7
0
0
0
% K
% Leu:
88
0
82
0
0
7
0
0
0
0
7
0
0
0
0
% L
% Met:
13
7
19
0
0
0
0
0
0
7
0
0
19
0
0
% M
% Asn:
0
0
0
0
0
7
0
0
13
7
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% P
% Gln:
0
0
0
0
7
44
0
0
0
0
38
0
0
0
0
% Q
% Arg:
0
82
0
0
82
13
0
7
0
7
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
7
0
13
7
0
0
0
13
% S
% Thr:
0
0
0
0
0
7
0
82
0
0
7
0
0
0
25
% T
% Val:
0
7
0
7
0
0
0
0
0
0
0
0
57
38
50
% V
% Trp:
0
0
0
0
7
0
7
0
0
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
69
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _