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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L2
All Species:
28.48
Human Site:
T401
Identified Species:
41.78
UniProt:
Q8IUZ5
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUZ5
NP_699204.1
450
49711
T401
E
N
Y
V
L
L
S
T
D
G
P
G
R
N
I
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
A401
E
K
R
V
L
L
S
A
D
G
P
H
R
N
V
Rhesus Macaque
Macaca mulatta
XP_001095786
450
49770
T401
E
N
Y
V
L
L
S
T
D
G
P
G
R
N
I
Dog
Lupus familis
XP_538569
450
49862
T401
D
Y
Y
I
L
L
S
T
D
G
P
G
R
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1K4
467
51947
I401
E
N
Y
I
L
L
S
I
D
G
P
G
K
N
I
Rat
Rattus norvegicus
Q64565
512
57182
C462
V
N
Q
I
H
E
D
C
K
D
M
G
L
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518367
451
50169
T401
T
D
Y
I
L
L
S
T
D
G
P
G
R
N
V
Chicken
Gallus gallus
XP_414688
533
59234
T483
E
E
Y
I
L
L
S
T
D
G
P
G
R
N
V
Frog
Xenopus laevis
Q6DEB1
509
56952
A402
E
K
R
I
L
L
S
A
D
G
P
Y
R
N
V
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
A403
E
Q
R
I
L
L
S
A
D
G
P
H
R
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
S414
Q
L
H
R
V
L
V
S
S
D
G
P
N
D
N
Honey Bee
Apis mellifera
XP_392348
482
53855
S408
D
R
K
I
L
I
S
S
D
G
P
D
D
N
I
Nematode Worm
Caenorhab. elegans
P91408
467
51626
T416
D
Q
K
L
A
I
A
T
I
L
A
L
R
K
S
Sea Urchin
Strong. purpuratus
XP_793741
543
60687
S404
E
M
H
I
L
F
S
S
E
G
P
F
E
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
S426
T
P
A
K
A
E
T
S
V
L
F
E
Q
L
R
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
V354
S
N
G
I
I
S
E
V
R
G
M
G
L
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.1
96.8
87.7
N.A.
83.9
31.8
N.A.
81.3
64.1
56.5
57.1
N.A.
47.3
53.3
44.1
45.6
Protein Similarity:
100
74.9
98.4
94.6
N.A.
89.9
49.6
N.A.
90.9
75
73.4
73.3
N.A.
66.5
72.6
65
62
P-Site Identity:
100
66.6
100
73.3
N.A.
80
13.3
N.A.
73.3
80
60
60
N.A.
6.6
46.6
13.3
46.6
P-Site Similarity:
100
73.3
100
93.3
N.A.
93.3
26.6
N.A.
93.3
93.3
73.3
73.3
N.A.
40
73.3
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
13
0
7
19
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
19
7
0
0
0
0
7
0
63
13
0
7
7
7
0
% D
% Glu:
50
7
0
0
0
13
7
0
7
0
0
7
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
7
7
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
75
7
50
0
0
0
% G
% His:
0
0
13
0
7
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
0
0
63
7
13
0
7
7
0
0
0
0
0
32
% I
% Lys:
0
13
13
7
0
0
0
0
7
0
0
0
7
7
0
% K
% Leu:
0
7
0
7
69
63
0
0
0
13
0
7
13
19
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
32
0
0
0
0
0
0
0
0
0
0
7
69
7
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
69
7
0
0
0
% P
% Gln:
7
13
7
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
7
19
7
0
0
0
0
7
0
0
0
57
0
7
% R
% Ser:
7
0
0
0
0
7
69
25
7
0
0
0
0
0
7
% S
% Thr:
13
0
0
0
0
0
7
38
0
0
0
0
0
0
7
% T
% Val:
7
0
0
19
7
0
7
7
7
0
0
0
0
0
44
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
38
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _