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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGXT2L2 All Species: 21.52
Human Site: Y396 Identified Species: 31.56
UniProt: Q8IUZ5 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IUZ5 NP_699204.1 450 49711 Y396 V S R L K E N Y V L L S T D G
Chimpanzee Pan troglodytes XP_001137764 499 55702 R396 I Y K M K E K R V L L S A D G
Rhesus Macaque Macaca mulatta XP_001095786 450 49770 Y396 V S R L K E N Y V L L S T D G
Dog Lupus familis XP_538569 450 49862 Y396 V S R L K D Y Y I L L S T D G
Cat Felis silvestris
Mouse Mus musculus Q8R1K4 467 51947 Y396 V S R L K E N Y I L L S I D G
Rat Rattus norvegicus Q64565 512 57182 Q457 L P K T E V N Q I H E D C K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518367 451 50169 Y396 V S R L K T D Y I L L S T D G
Chicken Gallus gallus XP_414688 533 59234 Y478 I T R L K E E Y I L L S T D G
Frog Xenopus laevis Q6DEB1 509 56952 R397 I Y K L K E K R I L L S A D G
Zebra Danio Brachydanio rerio Q7SY54 492 54717 R398 I Y R L K E Q R I L L S A D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VU95 494 54265 H409 V N R M K Q L H R V L V S S D
Honey Bee Apis mellifera XP_392348 482 53855 K403 V S R M K D R K I L I S S D G
Nematode Worm Caenorhab. elegans P91408 467 51626 K411 N T R E P D Q K L A I A T I L
Sea Urchin Strong. purpuratus XP_793741 543 60687 H399 I K R L R E M H I L F S S E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q940M2 476 51934 A421 D R K D K T P A K A E T S V L
Baker's Yeast Sacchar. cerevisiae P07991 424 46067 G349 A L Q A K S N G I I S E V R G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.1 96.8 87.7 N.A. 83.9 31.8 N.A. 81.3 64.1 56.5 57.1 N.A. 47.3 53.3 44.1 45.6
Protein Similarity: 100 74.9 98.4 94.6 N.A. 89.9 49.6 N.A. 90.9 75 73.4 73.3 N.A. 66.5 72.6 65 62
P-Site Identity: 100 53.3 100 80 N.A. 86.6 6.6 N.A. 80 73.3 53.3 60 N.A. 26.6 53.3 13.3 40
P-Site Similarity: 100 73.3 100 93.3 N.A. 93.3 33.3 N.A. 93.3 93.3 73.3 73.3 N.A. 66.6 86.6 46.6 80
Percent
Protein Identity: N.A. N.A. N.A. 38.8 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. 56.9 47.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 0 0 0 7 0 13 0 7 19 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 7 0 0 7 0 19 7 0 0 0 0 7 0 63 13 % D
% Glu: 0 0 0 7 7 50 7 0 0 0 13 7 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 75 % G
% His: 0 0 0 0 0 0 0 13 0 7 0 0 0 0 0 % H
% Ile: 32 0 0 0 0 0 0 0 63 7 13 0 7 7 0 % I
% Lys: 0 7 25 0 82 0 13 13 7 0 0 0 0 7 0 % K
% Leu: 7 7 0 57 0 0 7 0 7 69 63 0 0 0 13 % L
% Met: 0 0 0 19 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 7 7 0 0 0 0 32 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 7 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 7 13 7 0 0 0 0 0 0 0 % Q
% Arg: 0 7 69 0 7 0 7 19 7 0 0 0 0 7 0 % R
% Ser: 0 38 0 0 0 7 0 0 0 0 7 69 25 7 0 % S
% Thr: 0 13 0 7 0 13 0 0 0 0 0 7 38 0 0 % T
% Val: 44 0 0 0 0 7 0 0 19 7 0 7 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 19 0 0 0 0 7 38 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _