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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGXT2L2
All Species:
40
Human Site:
Y92
Identified Species:
58.67
UniProt:
Q8IUZ5
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUZ5
NP_699204.1
450
49711
Y92
L
H
D
N
I
V
D
Y
A
Q
R
L
S
E
T
Chimpanzee
Pan troglodytes
XP_001137764
499
55702
Y91
L
H
D
N
I
V
E
Y
A
K
R
L
S
A
T
Rhesus Macaque
Macaca mulatta
XP_001095786
450
49770
Y92
L
H
D
N
I
V
D
Y
A
Q
R
L
S
E
T
Dog
Lupus familis
XP_538569
450
49862
Y92
L
H
D
N
I
V
D
Y
A
Q
R
L
S
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1K4
467
51947
Y92
L
H
D
N
I
V
D
Y
A
Q
R
L
S
E
T
Rat
Rattus norvegicus
Q64565
512
57182
Y147
F
H
S
P
M
H
E
Y
A
E
R
L
S
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518367
451
50169
Y92
L
H
D
N
M
V
D
Y
A
Q
R
L
S
E
T
Chicken
Gallus gallus
XP_414688
533
59234
Y174
L
H
D
N
L
T
D
Y
A
E
R
L
S
E
K
Frog
Xenopus laevis
Q6DEB1
509
56952
Y91
L
H
D
N
L
V
R
Y
A
E
C
L
I
S
T
Zebra Danio
Brachydanio rerio
Q7SY54
492
54717
Y92
L
H
D
S
L
V
L
Y
A
Q
R
L
Q
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VU95
494
54265
C102
L
H
D
E
L
V
Q
C
A
R
T
L
T
S
K
Honey Bee
Apis mellifera
XP_392348
482
53855
C94
L
H
D
D
L
V
I
C
A
R
R
L
T
S
L
Nematode Worm
Caenorhab. elegans
P91408
467
51626
D110
F
V
S
T
Q
L
T
D
C
A
E
Q
I
L
S
Sea Urchin
Strong. purpuratus
XP_793741
543
60687
Y94
L
Y
D
Q
M
V
L
Y
A
Q
R
L
T
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q940M2
476
51934
F142
L
H
H
A
I
G
D
F
A
E
A
L
A
A
K
Baker's Yeast
Sacchar. cerevisiae
P07991
424
46067
A89
A
F
H
N
D
V
Y
A
Q
F
A
K
F
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.1
96.8
87.7
N.A.
83.9
31.8
N.A.
81.3
64.1
56.5
57.1
N.A.
47.3
53.3
44.1
45.6
Protein Similarity:
100
74.9
98.4
94.6
N.A.
89.9
49.6
N.A.
90.9
75
73.4
73.3
N.A.
66.5
72.6
65
62
P-Site Identity:
100
80
100
100
N.A.
100
40
N.A.
93.3
73.3
60
66.6
N.A.
40
46.6
0
60
P-Site Similarity:
100
93.3
100
100
N.A.
100
60
N.A.
100
86.6
73.3
80
N.A.
60
73.3
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.8
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
56.9
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
7
88
7
13
0
7
25
0
% A
% Cys:
0
0
0
0
0
0
0
13
7
0
7
0
0
0
0
% C
% Asp:
0
0
75
7
7
0
44
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
7
0
0
13
0
0
25
7
0
0
38
0
% E
% Phe:
13
7
0
0
0
0
0
7
0
7
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
82
13
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
38
0
7
0
0
0
0
0
13
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
19
% K
% Leu:
82
0
0
0
32
7
13
0
0
0
0
88
0
7
13
% L
% Met:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
57
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
7
0
7
44
0
7
7
7
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
13
69
0
0
0
0
% R
% Ser:
0
0
13
7
0
0
0
0
0
0
0
0
50
19
7
% S
% Thr:
0
0
0
7
0
7
7
0
0
0
7
0
19
0
63
% T
% Val:
0
7
0
0
0
75
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
69
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _