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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT12
All Species:
22.73
Human Site:
S108
Identified Species:
45.45
UniProt:
Q8IV01
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IV01
NP_808878.1
421
46537
S108
E
D
T
F
E
S
I
S
E
L
G
P
L
E
L
Chimpanzee
Pan troglodytes
XP_001172576
455
50155
S143
E
D
T
F
E
S
I
S
E
L
G
P
L
E
L
Rhesus Macaque
Macaca mulatta
XP_001117977
421
46453
S108
E
D
T
F
E
S
I
S
E
L
G
P
L
E
L
Dog
Lupus familis
XP_540824
437
48192
S124
E
D
T
F
E
S
I
S
E
L
G
P
L
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q920N7
421
46662
S108
E
D
T
F
E
S
I
S
E
L
G
P
L
E
L
Rat
Rattus norvegicus
P97610
421
46590
S108
E
D
T
F
E
S
I
S
E
L
G
P
L
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P47191
424
47487
N105
K
G
G
K
N
A
I
N
M
K
D
V
K
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122205
420
46816
R108
L
D
T
P
D
G
L
R
D
L
G
T
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
F127
I
L
V
F
L
V
V
F
G
I
I
F
F
C
V
Honey Bee
Apis mellifera
XP_001121685
991
110251
N411
L
P
I
Y
D
S
I
N
E
L
G
L
H
Q
D
Nematode Worm
Caenorhab. elegans
P34693
441
49885
F117
K
K
G
G
L
K
G
F
F
G
K
G
Q
D
V
Sea Urchin
Strong. purpuratus
XP_784931
322
35947
L20
P
P
A
P
H
Q
N
L
S
G
I
S
G
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
97.3
91.7
N.A.
95
95.9
N.A.
N.A.
23.5
N.A.
66.2
N.A.
24.8
21.2
22.6
34.4
Protein Similarity:
100
92.3
98.5
94
N.A.
97.3
97.8
N.A.
N.A.
45.2
N.A.
81.4
N.A.
43.2
31.6
45.1
51.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
46.6
N.A.
6.6
33.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
40
N.A.
66.6
N.A.
26.6
60
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
9
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
59
0
0
17
0
0
0
9
0
9
0
0
17
9
% D
% Glu:
50
0
0
0
50
0
0
0
59
0
0
0
0
59
0
% E
% Phe:
0
0
0
59
0
0
0
17
9
0
0
9
9
0
0
% F
% Gly:
0
9
17
9
0
9
9
0
9
17
67
9
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
9
0
0
0
67
0
0
9
17
0
0
0
0
% I
% Lys:
17
9
0
9
0
9
0
0
0
9
9
0
9
0
0
% K
% Leu:
17
9
0
0
17
0
9
9
0
67
0
9
59
0
67
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
9
17
0
0
0
0
0
0
0
% N
% Pro:
9
17
0
17
0
0
0
0
0
0
0
50
0
0
9
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
9
9
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
59
0
50
9
0
0
9
0
0
0
% S
% Thr:
0
0
59
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
0
9
9
0
0
0
0
9
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _