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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT12 All Species: 21.82
Human Site: S238 Identified Species: 43.64
UniProt: Q8IV01 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV01 NP_808878.1 421 46537 S238 E E K S L R F S V F G I D E D
Chimpanzee Pan troglodytes XP_001172576 455 50155 V273 E K S L R F S V F G I D E D E
Rhesus Macaque Macaca mulatta XP_001117977 421 46453 S238 E Q K S L R F S V F G I D E D
Dog Lupus familis XP_540824 437 48192 S254 E E K S L R F S V F G I D E D
Cat Felis silvestris
Mouse Mus musculus Q920N7 421 46662 S238 E E K S L R F S V F G I D E D
Rat Rattus norvegicus P97610 421 46590 S238 E E K S L R F S V F G I D E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P47191 424 47487 A230 G G K T L V M A V Y D F D R F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122205 420 46816 S237 E E N S L R F S T F G V D S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 A279 M N K T L V F A I F D F D R F
Honey Bee Apis mellifera XP_001121685 991 110251 V640 R K R N D F Y V A V E E V Q L
Nematode Worm Caenorhab. elegans P34693 441 49885 A245 T A K T L V F A I Y D F D R F
Sea Urchin Strong. purpuratus XP_784931 322 35947 L145 L P R R T L R L T V M N Y D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 97.3 91.7 N.A. 95 95.9 N.A. N.A. 23.5 N.A. 66.2 N.A. 24.8 21.2 22.6 34.4
Protein Similarity: 100 92.3 98.5 94 N.A. 97.3 97.8 N.A. N.A. 45.2 N.A. 81.4 N.A. 43.2 31.6 45.1 51.5
P-Site Identity: 100 6.6 93.3 100 N.A. 100 100 N.A. N.A. 26.6 N.A. 73.3 N.A. 33.3 0 26.6 0
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. N.A. 46.6 N.A. 80 N.A. 53.3 33.3 53.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 25 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 25 9 75 17 50 % D
% Glu: 59 42 0 0 0 0 0 0 0 0 9 9 9 42 9 % E
% Phe: 0 0 0 0 0 17 67 0 9 59 0 25 0 0 25 % F
% Gly: 9 9 0 0 0 0 0 0 0 9 50 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 9 42 0 0 0 % I
% Lys: 0 17 67 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 9 75 9 0 9 0 0 0 0 0 0 9 % L
% Met: 9 0 0 0 0 0 9 0 0 0 9 0 0 0 0 % M
% Asn: 0 9 9 9 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 17 9 9 50 9 0 0 0 0 0 0 25 9 % R
% Ser: 0 0 9 50 0 0 9 50 0 0 0 0 0 9 0 % S
% Thr: 9 0 0 25 9 0 0 0 17 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 25 0 17 50 17 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 17 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _