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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYT12
All Species:
24.85
Human Site:
S250
Identified Species:
49.7
UniProt:
Q8IV01
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IV01
NP_808878.1
421
46537
S250
D
E
D
E
R
N
V
S
T
G
V
V
E
L
K
Chimpanzee
Pan troglodytes
XP_001172576
455
50155
T285
E
D
E
R
N
V
S
T
G
V
V
E
L
K
L
Rhesus Macaque
Macaca mulatta
XP_001117977
421
46453
S250
D
E
D
E
R
N
V
S
T
G
V
V
E
L
K
Dog
Lupus familis
XP_540824
437
48192
S266
D
E
D
E
R
N
V
S
T
G
V
V
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q920N7
421
46662
S250
D
E
D
E
R
N
V
S
T
G
V
V
E
L
K
Rat
Rattus norvegicus
P97610
421
46590
S250
D
E
D
E
R
N
V
S
T
G
V
V
E
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P47191
424
47487
I242
D
R
F
S
K
H
D
I
I
G
E
Y
K
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122205
420
46816
T249
D
S
D
E
R
N
I
T
A
G
V
A
E
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P21521
474
53246
Q291
D
R
F
S
K
H
D
Q
I
G
E
V
K
V
P
Honey Bee
Apis mellifera
XP_001121685
991
110251
S652
V
Q
L
K
R
K
F
S
Q
S
F
I
T
N
Y
Nematode Worm
Caenorhab. elegans
P34693
441
49885
Q257
D
R
F
S
K
H
D
Q
I
G
Q
V
L
I
P
Sea Urchin
Strong. purpuratus
XP_784931
322
35947
E157
Y
D
R
H
A
R
H
E
E
I
G
Q
T
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
97.3
91.7
N.A.
95
95.9
N.A.
N.A.
23.5
N.A.
66.2
N.A.
24.8
21.2
22.6
34.4
Protein Similarity:
100
92.3
98.5
94
N.A.
97.3
97.8
N.A.
N.A.
45.2
N.A.
81.4
N.A.
43.2
31.6
45.1
51.5
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
66.6
N.A.
20
13.3
20
0
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
N.A.
40
N.A.
80
N.A.
46.6
33.3
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
17
50
0
0
0
25
0
0
0
0
0
0
0
0
% D
% Glu:
9
42
9
50
0
0
0
9
9
0
17
9
50
9
0
% E
% Phe:
0
0
25
0
0
0
9
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
9
75
9
0
0
0
0
% G
% His:
0
0
0
9
0
25
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
25
9
0
9
0
9
0
% I
% Lys:
0
0
0
9
25
9
0
0
0
0
0
0
17
9
50
% K
% Leu:
0
0
9
0
0
0
0
0
0
0
0
0
17
50
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
50
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
9
0
0
0
0
0
17
9
0
9
9
0
0
0
% Q
% Arg:
0
25
9
9
59
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
0
25
0
0
9
50
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
42
0
0
0
17
0
0
% T
% Val:
9
0
0
0
0
9
42
0
0
9
59
59
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _