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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT12 All Species: 26.97
Human Site: S45 Identified Species: 53.94
UniProt: Q8IV01 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV01 NP_808878.1 421 46537 S45 S L W K L W T S G S F P S P S
Chimpanzee Pan troglodytes XP_001172576 455 50155 S80 S L W K L W T S G S F P S P S
Rhesus Macaque Macaca mulatta XP_001117977 421 46453 S45 S L W K L W T S G S F P S P S
Dog Lupus familis XP_540824 437 48192 S61 S L W K L W T S G N F P S P S
Cat Felis silvestris
Mouse Mus musculus Q920N7 421 46662 S45 S L W K L W T S G S F P S P S
Rat Rattus norvegicus P97610 421 46590 S45 S L W K L W T S G S F P S P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P47191 424 47487 L45 K E D A F S N L K K K F M N E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122205 420 46816 S48 N L W R L Y K S G T F P T P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 E51 E V D R Q E Q E V L A E K A A
Honey Bee Apis mellifera XP_001121685 991 110251 K343 Y G S E E L S K M L Q S T Q S
Nematode Worm Caenorhab. elegans P34693 441 49885 V50 T K E T L K D V V V N K V I D
Sea Urchin Strong. purpuratus XP_784931 322 35947
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 97.3 91.7 N.A. 95 95.9 N.A. N.A. 23.5 N.A. 66.2 N.A. 24.8 21.2 22.6 34.4
Protein Similarity: 100 92.3 98.5 94 N.A. 97.3 97.8 N.A. N.A. 45.2 N.A. 81.4 N.A. 43.2 31.6 45.1 51.5
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. N.A. 0 N.A. 60 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 0 N.A. 93.3 N.A. 20 26.6 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 9 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 17 0 0 0 9 0 0 0 0 0 0 0 9 % D
% Glu: 9 9 9 9 9 9 0 9 0 0 0 9 0 0 9 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 59 9 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 59 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 9 9 0 50 0 9 9 9 9 9 9 9 9 0 0 % K
% Leu: 0 59 0 0 67 9 0 9 0 17 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % M
% Asn: 9 0 0 0 0 0 9 0 0 9 9 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 59 0 59 0 % P
% Gln: 0 0 0 0 9 0 9 0 0 0 9 0 0 9 0 % Q
% Arg: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 9 0 0 9 9 59 0 42 0 9 50 0 67 % S
% Thr: 9 0 0 9 0 0 50 0 0 9 0 0 17 0 0 % T
% Val: 0 9 0 0 0 0 0 9 17 9 0 0 9 0 0 % V
% Trp: 0 0 59 0 0 50 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _