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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT12 All Species: 20.61
Human Site: T88 Identified Species: 41.21
UniProt: Q8IV01 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV01 NP_808878.1 421 46537 T88 W N A Q R A S T R G P P S R K
Chimpanzee Pan troglodytes XP_001172576 455 50155 T123 W N A Q R A S T R G P P S R K
Rhesus Macaque Macaca mulatta XP_001117977 421 46453 T88 W N A Q R A S T R G S S S R K
Dog Lupus familis XP_540824 437 48192 T104 W N T Q R A S T R G P H S R K
Cat Felis silvestris
Mouse Mus musculus Q920N7 421 46662 T88 W N D Q R T T T R G P P S R K
Rat Rattus norvegicus P97610 421 46590 T88 W N A Q R T T T R G P P S R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P47191 424 47487 C85 C F C L C K K C L F K K K N K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122205 420 46816 R88 V A A C N Q R R A S S A S R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 R107 V T E V I A E R T G L P T W G
Honey Bee Apis mellifera XP_001121685 991 110251 L391 L F R E S Q G L Q K V S Q Y I
Nematode Worm Caenorhab. elegans P34693 441 49885 R97 A C A F C L I R K L F G K K R
Sea Urchin Strong. purpuratus XP_784931 322 35947
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 97.3 91.7 N.A. 95 95.9 N.A. N.A. 23.5 N.A. 66.2 N.A. 24.8 21.2 22.6 34.4
Protein Similarity: 100 92.3 98.5 94 N.A. 97.3 97.8 N.A. N.A. 45.2 N.A. 81.4 N.A. 43.2 31.6 45.1 51.5
P-Site Identity: 100 100 86.6 86.6 N.A. 80 86.6 N.A. N.A. 6.6 N.A. 26.6 N.A. 20 0 6.6 0
P-Site Similarity: 100 100 86.6 86.6 N.A. 86.6 93.3 N.A. N.A. 6.6 N.A. 26.6 N.A. 26.6 13.3 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 50 0 0 42 0 0 9 0 0 9 0 0 0 % A
% Cys: 9 9 9 9 17 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 9 9 0 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 17 0 9 0 0 0 0 0 9 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 59 0 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 9 9 0 9 9 9 9 17 9 67 % K
% Leu: 9 0 0 9 0 9 0 9 9 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 50 0 0 9 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 42 42 0 0 0 % P
% Gln: 0 0 0 50 0 17 0 0 9 0 0 0 9 0 0 % Q
% Arg: 0 0 9 0 50 0 9 25 50 0 0 0 0 59 9 % R
% Ser: 0 0 0 0 9 0 34 0 0 9 17 17 59 0 0 % S
% Thr: 0 9 9 0 0 17 17 50 9 0 0 0 9 0 0 % T
% Val: 17 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 50 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _