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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI1 All Species: 24.55
Human Site: S232 Identified Species: 49.09
UniProt: Q8IV48 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV48 NP_699163.2 349 40064 S232 Y S L L T D G S W D M S K F L
Chimpanzee Pan troglodytes XP_001136735 349 39985 S232 Y S L L T D G S W D M S K F L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539997 349 40208 S232 Y C I L T D G S W D M S K F L
Cat Felis silvestris
Mouse Mus musculus Q7TMF2 345 39475 S228 Y C I L T D G S W D M S K F L
Rat Rattus norvegicus Q5FVR4 345 39562 S228 Y C I L T D G S W D M S K F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508919 467 52517 S350 Y S I L T D G S W D M S K F L
Chicken Gallus gallus NP_001006450 327 37784 S224 L N I Q C R V S R I K H P S F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44406 582 67195 P253 F A F V T D G P H D M W K F M
Sea Urchin Strong. purpuratus XP_001186993 407 46052 S308 K G L G S K H S F A I A T D C
Poplar Tree Populus trichocarpa XP_002303940 399 46031 N226 F A V V T W S N W D C R V M L
Maize Zea mays NP_001146741 427 49102 N229 F A I V T W S N W D C R I M L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W566 337 38652 N232 A A F V T C G N W D I K T K I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 91.9 N.A. 83.3 84.2 N.A. 61 72.7 N.A. N.A. N.A. N.A. N.A. 22.6 37.3
Protein Similarity: 100 99.4 N.A. 95.1 N.A. 89.9 90.2 N.A. 66.1 83.3 N.A. N.A. N.A. N.A. N.A. 35.5 54.5
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 93.3 6.6 N.A. N.A. N.A. N.A. N.A. 46.6 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 100 20 N.A. N.A. N.A. N.A. N.A. 73.3 40
Percent
Protein Identity: 25 26.9 N.A. 22.3 N.A. N.A.
Protein Similarity: 41.3 42.6 N.A. 40.6 N.A. N.A.
P-Site Identity: 26.6 26.6 N.A. 26.6 N.A. N.A.
P-Site Similarity: 60 60 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 34 0 0 0 0 0 0 0 9 0 9 0 0 0 % A
% Cys: 0 25 0 0 9 9 0 0 0 0 17 0 0 0 9 % C
% Asp: 0 0 0 0 0 59 0 0 0 84 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 25 0 17 0 0 0 0 0 9 0 0 0 0 59 9 % F
% Gly: 0 9 0 9 0 0 67 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 9 0 0 9 0 0 0 % H
% Ile: 0 0 50 0 0 0 0 0 0 9 17 0 9 0 9 % I
% Lys: 9 0 0 0 0 9 0 0 0 0 9 9 59 9 0 % K
% Leu: 9 0 25 50 0 0 0 0 0 0 0 0 0 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 59 0 0 17 9 % M
% Asn: 0 9 0 0 0 0 0 25 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 9 0 0 17 0 0 0 % R
% Ser: 0 25 0 0 9 0 17 67 0 0 0 50 0 9 0 % S
% Thr: 0 0 0 0 84 0 0 0 0 0 0 0 17 0 0 % T
% Val: 0 0 9 34 0 0 9 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 17 0 0 75 0 0 9 0 0 0 % W
% Tyr: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _