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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERI1
All Species:
27.27
Human Site:
S246
Identified Species:
54.55
UniProt:
Q8IV48
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IV48
NP_699163.2
349
40064
S246
L
N
I
Q
C
Q
L
S
R
L
K
Y
P
P
F
Chimpanzee
Pan troglodytes
XP_001136735
349
39985
S246
L
N
I
Q
C
Q
L
S
R
L
K
Y
P
P
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539997
349
40208
S246
L
N
I
Q
C
R
L
S
R
L
K
Y
P
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMF2
345
39475
S242
L
S
I
Q
C
R
L
S
R
L
K
H
P
A
F
Rat
Rattus norvegicus
Q5FVR4
345
39562
S242
L
N
I
Q
C
Q
L
S
R
L
K
Y
P
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508919
467
52517
S364
L
T
I
Q
C
R
I
S
H
L
K
Y
P
A
F
Chicken
Gallus gallus
NP_001006450
327
37784
I238
F
A
K
K
W
I
N
I
R
K
S
Y
G
N
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44406
582
67195
S267
M
Q
F
Q
C
L
L
S
N
I
R
M
P
H
M
Sea Urchin
Strong. purpuratus
XP_001186993
407
46052
Y322
C
S
L
D
M
D
L
Y
L
K
L
Q
C
L
V
Poplar Tree
Populus trichocarpa
XP_002303940
399
46031
K240
L
E
S
E
C
R
F
K
K
I
R
K
P
P
Y
Maize
Zea mays
NP_001146741
427
49102
K243
L
E
S
E
C
R
F
K
R
I
R
K
P
P
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W566
337
38652
S246
I
P
E
Q
C
V
V
S
N
I
N
L
P
P
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
91.9
N.A.
83.3
84.2
N.A.
61
72.7
N.A.
N.A.
N.A.
N.A.
N.A.
22.6
37.3
Protein Similarity:
100
99.4
N.A.
95.1
N.A.
89.9
90.2
N.A.
66.1
83.3
N.A.
N.A.
N.A.
N.A.
N.A.
35.5
54.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
73.3
93.3
N.A.
66.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
80
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
20
Percent
Protein Identity:
25
26.9
N.A.
22.3
N.A.
N.A.
Protein Similarity:
41.3
42.6
N.A.
40.6
N.A.
N.A.
P-Site Identity:
26.6
33.3
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
66.6
66.6
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
17
0
% A
% Cys:
9
0
0
0
84
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
17
9
17
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
9
0
0
0
17
0
0
0
0
0
0
0
59
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% H
% Ile:
9
0
50
0
0
9
9
9
0
34
0
0
0
0
0
% I
% Lys:
0
0
9
9
0
0
0
17
9
17
50
17
0
0
0
% K
% Leu:
67
0
9
0
0
9
59
0
9
50
9
9
0
9
0
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
34
0
0
0
0
9
0
17
0
9
0
0
9
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
84
50
0
% P
% Gln:
0
9
0
67
0
25
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
42
0
0
59
0
25
0
0
0
0
% R
% Ser:
0
17
17
0
0
0
0
67
0
0
9
0
0
9
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
50
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _