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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI1 All Species: 28.18
Human Site: S333 Identified Species: 56.36
UniProt: Q8IV48 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV48 NP_699163.2 349 40064 S333 Q L M S V S S S L P I E G T P
Chimpanzee Pan troglodytes XP_001136735 349 39985 S333 Q L M S V S S S L P I E G T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539997 349 40208 S333 Q L M S V S S S L P I E G T P
Cat Felis silvestris
Mouse Mus musculus Q7TMF2 345 39475 S329 Q L M S V S S S L P V E G A P
Rat Rattus norvegicus Q5FVR4 345 39562 S329 Q L M S V S S S L P V E G A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508919 467 52517 A451 Q L T S V T S A T P I E G M P
Chicken Gallus gallus NP_001006450 327 37784 S311 Q L M T V S S S T P L E G A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44406 582 67195 S530 E N L S N A P S L H E F P S S
Sea Urchin Strong. purpuratus XP_001186993 407 46052 D394 V A L Q L I E D G A E M K Y N
Poplar Tree Populus trichocarpa XP_002303940 399 46031 S321 M W N T T D S S L P C K Q S P
Maize Zea mays NP_001146741 427 49102 S316 F K F S I T N S L V W Q P A A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W566 337 38652 R319 A V L K L T A R R S K S N M R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 91.9 N.A. 83.3 84.2 N.A. 61 72.7 N.A. N.A. N.A. N.A. N.A. 22.6 37.3
Protein Similarity: 100 99.4 N.A. 95.1 N.A. 89.9 90.2 N.A. 66.1 83.3 N.A. N.A. N.A. N.A. N.A. 35.5 54.5
P-Site Identity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 66.6 73.3 N.A. N.A. N.A. N.A. N.A. 20 0
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 80 86.6 N.A. N.A. N.A. N.A. N.A. 46.6 13.3
Percent
Protein Identity: 25 26.9 N.A. 22.3 N.A. N.A.
Protein Similarity: 41.3 42.6 N.A. 40.6 N.A. N.A.
P-Site Identity: 33.3 20 N.A. 0 N.A. N.A.
P-Site Similarity: 53.3 46.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 9 9 9 0 9 0 0 0 34 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 9 0 0 0 17 59 0 0 0 % E
% Phe: 9 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 0 59 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 9 0 0 0 0 34 0 0 0 0 % I
% Lys: 0 9 0 9 0 0 0 0 0 0 9 9 9 0 0 % K
% Leu: 0 59 25 0 17 0 0 0 67 0 9 0 0 0 0 % L
% Met: 9 0 50 0 0 0 0 0 0 0 0 9 0 17 0 % M
% Asn: 0 9 9 0 9 0 9 0 0 0 0 0 9 0 9 % N
% Pro: 0 0 0 0 0 0 9 0 0 67 0 0 17 0 67 % P
% Gln: 59 0 0 9 0 0 0 0 0 0 0 9 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 9 % R
% Ser: 0 0 0 67 0 50 67 75 0 9 0 9 0 17 9 % S
% Thr: 0 0 9 17 9 25 0 0 17 0 0 0 0 25 0 % T
% Val: 9 9 0 0 59 0 0 0 0 9 17 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _