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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI1 All Species: 12.73
Human Site: S57 Identified Species: 25.45
UniProt: Q8IV48 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV48 NP_699163.2 349 40064 S57 G S K F I T S S A S D F S D P
Chimpanzee Pan troglodytes XP_001136735 349 39985 S57 G S K F I T S S A S D F S D P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539997 349 40208 S57 G S K F I T S S A S D F S D P
Cat Felis silvestris
Mouse Mus musculus Q7TMF2 345 39475 V61 G S D F S D P V Y K E I A M T
Rat Rattus norvegicus Q5FVR4 345 39562 V61 G G D F S D P V Y K E I A M T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508919 467 52517 G175 G K E P I S P G A S D F S D P
Chicken Gallus gallus NP_001006450 327 37784 M57 T N G Y I N R M T R D E L R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44406 582 67195 V73 Q L L P S E R V E P L K S M V
Sea Urchin Strong. purpuratus XP_001186993 407 46052 R140 Y Q A S S P S R S K D F S H P
Poplar Tree Populus trichocarpa XP_002303940 399 46031 E57 E F L E L P S E F Q N K P A Y
Maize Zea mays NP_001146741 427 49102 S57 A T P N Q G L S R P I Y R Q E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W566 337 38652 S58 P S D F S S S S S S S S S S P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 91.9 N.A. 83.3 84.2 N.A. 61 72.7 N.A. N.A. N.A. N.A. N.A. 22.6 37.3
Protein Similarity: 100 99.4 N.A. 95.1 N.A. 89.9 90.2 N.A. 66.1 83.3 N.A. N.A. N.A. N.A. N.A. 35.5 54.5
P-Site Identity: 100 100 N.A. 100 N.A. 20 13.3 N.A. 60 13.3 N.A. N.A. N.A. N.A. N.A. 6.6 33.3
P-Site Similarity: 100 100 N.A. 100 N.A. 33.3 26.6 N.A. 73.3 26.6 N.A. N.A. N.A. N.A. N.A. 6.6 40
Percent
Protein Identity: 25 26.9 N.A. 22.3 N.A. N.A.
Protein Similarity: 41.3 42.6 N.A. 40.6 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 46.6 N.A. N.A.
P-Site Similarity: 20 20 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 0 34 0 0 0 17 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 25 0 0 17 0 0 0 0 50 0 0 34 0 % D
% Glu: 9 0 9 9 0 9 0 9 9 0 17 9 0 0 9 % E
% Phe: 0 9 0 50 0 0 0 0 9 0 0 42 0 0 0 % F
% Gly: 50 9 9 0 0 9 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 42 0 0 0 0 0 9 17 0 0 0 % I
% Lys: 0 9 25 0 0 0 0 0 0 25 0 17 0 0 0 % K
% Leu: 0 9 17 0 9 0 9 0 0 0 9 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 25 0 % M
% Asn: 0 9 0 9 0 9 0 0 0 0 9 0 0 0 0 % N
% Pro: 9 0 9 17 0 17 25 0 0 17 0 0 9 0 50 % P
% Gln: 9 9 0 0 9 0 0 0 0 9 0 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 17 9 9 9 0 0 9 9 0 % R
% Ser: 0 42 0 9 42 17 50 42 17 42 9 9 59 9 9 % S
% Thr: 9 9 0 0 0 25 0 0 9 0 0 0 0 0 17 % T
% Val: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 9 0 0 0 0 17 0 0 9 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _