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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI1 All Species: 7.69
Human Site: S6 Identified Species: 15.38
UniProt: Q8IV48 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV48 NP_699163.2 349 40064 S6 _ _ M E D P Q S K E P A G E A
Chimpanzee Pan troglodytes XP_001136735 349 39985 S6 _ _ M E D P Q S K E P A G E A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539997 349 40208 S6 _ _ M E Q E R S T Q P G G E A
Cat Felis silvestris
Mouse Mus musculus Q7TMF2 345 39475 G10 D E R G R E R G G D A A Q Q K
Rat Rattus norvegicus Q5FVR4 345 39562 G10 D E R G R E H G G D A A Q Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508919 467 52517 A124 S S P P R Q Q A K D P G D Y V
Chicken Gallus gallus NP_001006450 327 37784 E6 _ _ M E E Q K E N R P Q A A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44406 582 67195 K22 E S L R D L L K I S Q E F D A
Sea Urchin Strong. purpuratus XP_001186993 407 46052 A89 D T V A S C V A S R V F K E G
Poplar Tree Populus trichocarpa XP_002303940 399 46031 E6 _ _ M Q R S C E A S L K C L Q
Maize Zea mays NP_001146741 427 49102 E6 _ _ M Q V N N E A P L G C L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W566 337 38652 A7 _ M A S A F S A F R V S L S R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 91.9 N.A. 83.3 84.2 N.A. 61 72.7 N.A. N.A. N.A. N.A. N.A. 22.6 37.3
Protein Similarity: 100 99.4 N.A. 95.1 N.A. 89.9 90.2 N.A. 66.1 83.3 N.A. N.A. N.A. N.A. N.A. 35.5 54.5
P-Site Identity: 100 100 N.A. 53.8 N.A. 6.6 6.6 N.A. 20 23 N.A. N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 100 N.A. 69.2 N.A. 26.6 20 N.A. 33.3 38.4 N.A. N.A. N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: 25 26.9 N.A. 22.3 N.A. N.A.
Protein Similarity: 41.3 42.6 N.A. 40.6 N.A. N.A.
P-Site Identity: 7.6 7.6 N.A. 0 N.A. N.A.
P-Site Similarity: 15.3 15.3 N.A. 14.2 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 0 0 25 17 0 17 34 9 9 34 % A
% Cys: 0 0 0 0 0 9 9 0 0 0 0 0 17 0 0 % C
% Asp: 25 0 0 0 25 0 0 0 0 25 0 0 9 9 0 % D
% Glu: 9 17 0 34 9 25 0 25 0 17 0 9 0 34 0 % E
% Phe: 0 0 0 0 0 9 0 0 9 0 0 9 9 0 0 % F
% Gly: 0 0 0 17 0 0 0 17 17 0 0 25 25 0 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 9 25 0 0 9 9 0 25 % K
% Leu: 0 0 9 0 0 9 9 0 0 0 17 0 9 17 0 % L
% Met: 0 9 50 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 9 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 9 9 0 17 0 0 0 9 42 0 0 0 0 % P
% Gln: 0 0 0 17 9 17 25 0 0 9 9 9 17 17 9 % Q
% Arg: 0 0 17 9 34 0 17 0 0 25 0 0 0 0 17 % R
% Ser: 9 17 0 9 9 9 9 25 9 17 0 9 0 9 0 % S
% Thr: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % T
% Val: 0 0 9 0 9 0 9 0 0 0 17 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 59 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % _