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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERI1 All Species: 20.3
Human Site: Y110 Identified Species: 40.61
UniProt: Q8IV48 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV48 NP_699163.2 349 40064 Y110 K K R L K N Y Y K K Q K L M L
Chimpanzee Pan troglodytes XP_001136735 349 39985 Y110 K K R L K N Y Y K K Q K L M L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539997 349 40208 Y110 K K R L K N Y Y K K Q K L M L
Cat Felis silvestris
Mouse Mus musculus Q7TMF2 345 39475 K114 K K Q K L M L K E S S A G D S
Rat Rattus norvegicus Q5FVR4 345 39562 K114 K K Q K L M L K E S N A V D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508919 467 52517 Y228 K K R L K N Y Y K K Q K L M Q
Chicken Gallus gallus NP_001006450 327 37784 V110 S Y Y D Y I C V V D F E A T C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44406 582 67195 Y126 R K R V A Q Y Y R K E N A L L
Sea Urchin Strong. purpuratus XP_001186993 407 46052 Y193 K R R L K D H Y S K E S L K M
Poplar Tree Populus trichocarpa XP_002303940 399 46031 F110 Q Y A P F N M F S Q G Y P C E
Maize Zea mays NP_001146741 427 49102 F110 N R V Q Y L P F K M L P Q G H
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W566 337 38652 L111 N H D C S K E L R V A A A D L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 91.9 N.A. 83.3 84.2 N.A. 61 72.7 N.A. N.A. N.A. N.A. N.A. 22.6 37.3
Protein Similarity: 100 99.4 N.A. 95.1 N.A. 89.9 90.2 N.A. 66.1 83.3 N.A. N.A. N.A. N.A. N.A. 35.5 54.5
P-Site Identity: 100 100 N.A. 100 N.A. 13.3 13.3 N.A. 93.3 0 N.A. N.A. N.A. N.A. N.A. 40 46.6
P-Site Similarity: 100 100 N.A. 100 N.A. 26.6 33.3 N.A. 93.3 6.6 N.A. N.A. N.A. N.A. N.A. 73.3 80
Percent
Protein Identity: 25 26.9 N.A. 22.3 N.A. N.A.
Protein Similarity: 41.3 42.6 N.A. 40.6 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 26.6 20 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 0 0 0 0 0 9 25 25 0 0 % A
% Cys: 0 0 0 9 0 0 9 0 0 0 0 0 0 9 9 % C
% Asp: 0 0 9 9 0 9 0 0 0 9 0 0 0 25 0 % D
% Glu: 0 0 0 0 0 0 9 0 17 0 17 9 0 0 9 % E
% Phe: 0 0 0 0 9 0 0 17 0 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 0 9 9 0 % G
% His: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 59 59 0 17 42 9 0 17 42 50 0 34 0 9 0 % K
% Leu: 0 0 0 42 17 9 17 9 0 0 9 0 42 9 42 % L
% Met: 0 0 0 0 0 17 9 0 0 9 0 0 0 34 9 % M
% Asn: 17 0 0 0 0 42 0 0 0 0 9 9 0 0 0 % N
% Pro: 0 0 0 9 0 0 9 0 0 0 0 9 9 0 0 % P
% Gln: 9 0 17 9 0 9 0 0 0 9 34 0 9 0 9 % Q
% Arg: 9 17 50 0 0 0 0 0 17 0 0 0 0 0 0 % R
% Ser: 9 0 0 0 9 0 0 0 17 17 9 9 0 0 17 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % T
% Val: 0 0 9 9 0 0 0 9 9 9 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 17 9 0 17 0 42 50 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _