KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK3
All Species:
5.45
Human Site:
S170
Identified Species:
15
UniProt:
Q8IV63
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IV63
NP_057524.3
474
52881
S170
G
R
Q
W
K
L
K
S
F
Q
T
R
D
N
Q
Chimpanzee
Pan troglodytes
XP_512840
474
52787
S170
G
Q
Q
W
E
L
K
S
L
Q
T
R
D
N
Q
Rhesus Macaque
Macaca mulatta
XP_001115913
482
53843
G171
T
V
L
T
D
K
S
G
R
Q
W
K
L
K
F
Dog
Lupus familis
XP_541482
457
51555
I170
I
L
Y
E
A
E
S
I
S
T
V
A
C
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3G5
453
50811
S170
E
P
T
S
A
V
P
S
E
S
R
T
Q
K
W
Rat
Rattus norvegicus
NP_001005561
453
50987
S170
E
P
T
S
A
I
S
S
E
S
R
T
Q
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233775
412
46333
D147
S
L
K
L
D
V
K
D
S
K
I
Y
N
E
Q
Frog
Xenopus laevis
NP_001086247
475
53551
K178
L
T
D
T
Q
S
V
K
W
R
L
A
K
F
L
Zebra Danio
Brachydanio rerio
NP_001013586
459
51260
V178
L
W
K
T
E
L
D
V
T
Y
G
V
C
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.3
76.3
N.A.
72.1
72.3
N.A.
N.A.
43
43.5
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
94.6
82.4
N.A.
81.8
82
N.A.
N.A.
55.2
59.3
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
6.6
0
N.A.
6.6
6.6
N.A.
N.A.
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
13.3
0
N.A.
13.3
13.3
N.A.
N.A.
40
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
0
0
0
0
0
23
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% C
% Asp:
0
0
12
0
23
0
12
12
0
0
0
0
23
0
0
% D
% Glu:
23
0
0
12
23
12
0
0
23
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
12
% F
% Gly:
23
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
12
0
12
0
0
12
0
0
0
0
% I
% Lys:
0
0
23
0
12
12
34
12
0
12
0
12
12
45
0
% K
% Leu:
23
23
12
12
0
34
0
0
12
0
12
0
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
23
0
% N
% Pro:
0
23
0
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
23
0
12
0
0
0
0
34
0
0
23
12
34
% Q
% Arg:
0
12
0
0
0
0
0
0
12
12
23
23
0
0
0
% R
% Ser:
12
0
0
23
0
12
34
45
23
23
0
0
0
0
12
% S
% Thr:
12
12
23
34
0
0
0
0
12
12
23
23
0
0
0
% T
% Val:
0
12
0
0
0
23
12
12
0
0
12
12
0
0
0
% V
% Trp:
0
12
0
23
0
0
0
0
12
0
12
0
0
0
23
% W
% Tyr:
0
0
12
0
0
0
0
0
0
12
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _