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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VRK3
All Species:
20
Human Site:
S55
Identified Species:
55
UniProt:
Q8IV63
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IV63
NP_057524.3
474
52881
S55
S
K
R
G
L
N
S
S
F
E
T
S
P
K
K
Chimpanzee
Pan troglodytes
XP_512840
474
52787
S55
S
K
R
G
L
N
S
S
F
E
I
S
P
K
K
Rhesus Macaque
Macaca mulatta
XP_001115913
482
53843
S56
S
K
R
G
L
N
S
S
F
E
T
S
P
K
K
Dog
Lupus familis
XP_541482
457
51555
S55
S
R
R
Q
N
N
T
S
P
E
T
P
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3G5
453
50811
S55
S
R
R
D
L
N
S
S
F
E
T
S
P
K
K
Rat
Rattus norvegicus
NP_001005561
453
50987
S55
S
K
R
D
L
N
S
S
S
E
T
S
P
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233775
412
46333
E32
E
E
Q
Q
Q
Q
Q
E
E
E
P
P
R
V
C
Frog
Xenopus laevis
NP_001086247
475
53551
A63
P
T
T
R
K
T
S
A
R
K
C
S
Y
G
E
Zebra Danio
Brachydanio rerio
NP_001013586
459
51260
Q63
E
E
V
A
K
K
T
Q
S
I
L
S
Q
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.3
76.3
N.A.
72.1
72.3
N.A.
N.A.
43
43.5
36.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
94.6
82.4
N.A.
81.8
82
N.A.
N.A.
55.2
59.3
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
53.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
66.6
N.A.
93.3
86.6
N.A.
N.A.
20
33.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% C
% Asp:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
23
23
0
0
0
0
0
12
12
78
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
45
0
0
0
0
0
0
% F
% Gly:
0
0
0
34
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% I
% Lys:
0
45
0
0
23
12
0
0
0
12
0
0
0
67
67
% K
% Leu:
0
0
0
0
56
0
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
67
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
12
0
12
23
56
0
12
% P
% Gln:
0
0
12
23
12
12
12
12
0
0
0
0
12
0
0
% Q
% Arg:
0
23
67
12
0
0
0
0
12
0
0
0
12
0
0
% R
% Ser:
67
0
0
0
0
0
67
67
23
0
0
78
12
0
0
% S
% Thr:
0
12
12
0
0
12
23
0
0
0
56
0
0
12
0
% T
% Val:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _